RADIATION THERAPY IN THE TREATMENT OF NON-SMALL-CELL LUNG CANCER


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The paper considers the importance of radiotherapy in the combination treatment of patients with non-small-cell lung cancer (NSCLC). It describes different radiotherapy options and possibilities of combined treatments in patients with NSCLC.

Full Text

Restricted Access

About the authors

D. Gogolln

A.F. Tsyb Medical Radiology Research Center, Branch, National Medical RadiologyResearch Center, Ministry of Health of the Russian Federation

Email: dgogolin@yandex.ru

I. Gulidov

A.F. Tsyb Medical Radiology Research Center, Branch, National Medical RadiologyResearch Center, Ministry of Health of the Russian Federation

MD; Professor

Yu. Ragulln

A.F. Tsyb Medical Radiology Research Center, Branch, National Medical RadiologyResearch Center, Ministry of Health of the Russian Federation

Candidate of Medical Sciences

References

  1. http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx
  2. Давыдов М.И., Аксель Е.М. Статистика злокачественных новообразований в России и странах СНГ в 2010 г. / М.: РОНЦ, 2012.
  3. Злокачественные новообразования в России в 2013 году. Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой / М.: МНИОИ им. П.А. Герцена -филиал ФГБУ «ФМИЦ им. П.А. Герцена» Минздрава России, 2015; 250 с.
  4. Review on the tolerance of normal tissue to the therapeutic radiation // Int. J. Radiat. Oncol. Biol. Phys. - 2010; 76 (3): 1-120.
  5. Bral S., Gevaert T., Linthout N. et al. Prospective, risk-adapted strategy of stereotactic body radiotherapy for early-stage non-small-cell lung cancer: results of Phase II trial // Int. J. Rad. Oncol. Biol. Phys. - 2011; 80: 1314-49.
  6. Sashendra S., Haasbeek C., Slotman B. et al. Outcomes of stereotactic ablative radiotherapy for central lung tumors: A systematic review // Radioth. Oncol. - 2013; 106: 276-82.
  7. Бойко А.В., Черниченко А.В., Мещерякова И.А. и др. Лучевая терапия немелкоклеточного рака // Практ. онкол. - 2000; 3: 24-8.
  8. Cerfolio R., Bryant A., Cerfolio R. Pulmonary resection after concurrent chemotherapy and high dose (60 Gy) radiation for non-small cell lung cancer is safe and may provide increased survival // Eur. J. Cardiothorac. Surg. - 2009; 35 (4): 718-23.
  9. Kwong K., Edelman M., Suntharalingam M. et all. High-dose radiotherapy in trimodality treatment of Pancoast tumors results in high pathologic complete response rates and excellent long-term survival // J. Thorac. Cardiovasc. Surg. -2005; 129 (6): 1250-7.
  10. Воробьев А.В., Завьялов А.А., Добродеев А.Ю. и др. Комбинированное лечение рака легкого III стадией с интраоперационной лучевой терапией и радиосенсибилизацией // Сиб. онкол. журн. - 2009; Прил. 1: 75-6.
  11. Bradley J., Paulus R., Graham M. et al. Phase II trial of postoperative adjuvant paclitaxel/carboplatin and thoracic radiotherapy in resected stage II and IIIA non-small-cell lung cancer: promising long-term results of the Radiation Therapy Oncology Group - RTOG 9705 // J. Clin. Oncol. - 2005; 23 (15): 3480-7.
  12. Auperin A., Rolland E., Curran W. et al. Concomitant radiochemotherapy (RT-CT) versus sequential RT-CT in locally advanced non-small cell lung cancer (NSCLC): A meta-analysis using individual patient data (IPD) from randomized clinical trials (RCTs) // J. Thorac. Oncol. - 2007; 2: 310.
  13. Belderbos J., Uitterhoeve L., Belderbos H. et al. Randomised trial of sequential versus concurrent chemo-radiotherapy in patients with inoperable non-small cell lung cancer (EORTC 08972-22973) // Eur. J. Cancer. - 2007; 43: 114-21.
  14. Saunders M., Dische S., Barrett A. et al. Continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer: mature data from the randomised multicentre trial // Radioth. Oncol. - 1999; 52: 137-48.
  15. Belani C., Wang W., Johnson D. et al. Phase III study of the Eastern Cooperative Oncology Group (ECOG 2597): induction chemotherapy followed by either standard thoracic radiotherapy or hyperfractionated accelerated radiotherapy for patients with unresectable stage IIIA and B non-small-cell lung cancer // J. Clinic. Oncol. - 2005; 23 (16): 3760-7.
  16. Jeremic B., Milicic B., Milisavljevic S. Clinical prognostic factors in patients with locally advanced (stage III) non-small cell lung cancer treated with hyperfractionated radiation therapy with and without concurrent chemotherapy: single-Institution Experience in 600 patients // Cancer. - 2011; 117: 2995 -3003.
  17. Немкова Е.В., Мусс В.Ф. Лучевая терапия рака легкого с использованием методики нетрадиционного фракционирования и радиомодификации. Материалы Невского радиологического форума «Невские горизонты» / СПб, 2007; с. 680.
  18. Ильин М.А., Сотников В.М., Паньшин Г.А. и др. Результаты лучевой терапии немелкоклеточного рака легкого средними фракциями. Материалы IV Всеросс. нац. конгресса лучевых диагностов и терапевтов «Радиология-2010», 2010; с. 176.
  19. Гоголин Д.В., Гулидов И.А., Мардынский Ю.С. и др. Ускоренное гиперфракционирование с неравномерным дроблением дневной дозы при лучевом и химиолучевом лечении неоперабельного немелкоклеточного рака легкого // Сиб. онкол. журн. - 2014; 6: 5-9.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2016 Russkiy Vrach Publishing House

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies