AN ALGORITHM FOR SWITCHING FROM STIMULANT LAXATIVES TO OSMOTIC AGENTS


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The authors elaborated the management tactics for patients with chronic constipation, which included the use of polyethylene glycol (macrogol, Forlax) and the gradual reduction in the stimulant laxative until it was completely discontinued. The therapy was effective in 91.2% of the patients.

Full Text

Restricted Access

About the authors

T. Oganesyan

Moscow State University of Medicine and Dentistry

Email: proped@mail.ru
Candidate of Medical Sciences

Yu. Kucheryavyl

Moscow State University of Medicine and Dentistry

Email: proped@mail.ru
Candidate of Medical Sciences

S. Cheremushkln

Moscow State University of Medicine and Dentistry

Email: proped@mail.ru
Candidate of Medical Sciences

A. Goncharenko

Moscow State University of Medicine and Dentistry

Email: proped@mail.ru
Candidate of Medical Sciences

E. Barkalova

Moscow State University of Medicine and Dentistry

Email: proped@mail.ru

I. Maev

Moscow State University of Medicine and Dentistry

Email: proped@mail.ru
Professor Corresponding Member of the Academy of Russian Sciences

References

  1. Enck P., Leinert J., Smid M. et al. Prevalence of constipation in the German population - a representative survey (GECCO) // United Eur. Gastroenterol. J. -2016; 4 (3): 429-37.
  2. Казюлин А.Н., Кучерявый Ю.А. Практические и клинические аспекты синдрома хронического запора. Методическое руководство для врачей / М.: ВУНМЦ, 2005; 38 с.
  3. Pare P., Ferrazzi S., Thompson W. et al. An epidemiological survey of constipation in Canada: definitions, rates, demographics, and predictors of health care seeking // Am. J. Gastroenterol. - 2001; 96 (11): 3130-7.
  4. Mugie S., Di Lorenzo C., Benninga M. Constipation in childhood // Nat. Rev. Gastroenterol. Hepatol. - 2011; 8 (9): 502-11.
  5. Черемушкин С.В., Кучерявый Ю.А. Доказательная медицина и лечение хронического запора // Врач. - 2012; 10: 42-7.
  6. Flourié B., Not D., François C. et al. Factors associated with impaired quality of life in French patients with chronic idiopathic constipation: a cross-sectional study // Eur. J. Gastroenterol. Hepatol. - 2016; 28 (5): 525-31.
  7. Маевская Е.А., Кучерявый Ю.А., Маев И.В. Неалкогольная жировая болезнь печени и хронический запор: случайная или очевидная ассоциация в практике гастроэнтеролога? // Клин. перспективы гастроэнтерол., гепатол. -2015; 1: 27-36.
  8. Choung R., Rey E., Richard Locke G. 3rd. et al. Chronic constipation and co-morbidities: A prospective population-based nested case-control study // United Eur. Gastroenterol. J. - 2016; 4 (1): 142-51.
  9. Guérin A. et al. Risk of developing colorectal cancer and benign colorectal neoplasm in patients with chronic constipation // Aliment. Pharmacol. Ther. -2014; 40 (1): 83-92.
  10. Shin J., Jung H., Lee T. et al. Guidelines for the Diagnosis and Treatment of Chronic Functional Constipation in Korea, 2015 Revised Edition // J. Neurogastroenterol. Motil. - 2016; 22 (3): 383-411.
  11. Serra J., Mascort-Roca J., Marzo-Castillejo M. et al. Clinical practice guidelines for the management of constipation in adults. Part 2: Diagnosis and treatment // Gastroenterol. Hepatol. - 2016: S0210-5705(16)30004-8.
  12. Ивашкин В.Т., Абдулхаков С.Р., Баранская Е.К. и др. Клинические рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению взрослых пациентов с хроническим запором // РГГЖК. - 2014; 5: 69-75.
  13. Маев И.В., Маевская Е.А., Черемушкин С.В. и др. Реалии и перспективы лечения хронического запора // Клин. перспективы гастроэнтерол., гепатол. - 2014; 6: 30-6.
  14. Маев И., Андреев Д., Дичева Д. и др. Риск длительного применения слабительных препаратов // Врач. - 2014; 1: 26-30.
  15. Черемушкин С.В., Кучерявый Ю.А., Гончаренко А.Ю. и др. Ретроспективная оценка эффекта последействия полиэтиленгликоля при лечении хронического запора // Врач. - 2013; 3: 58-62.
  16. Johanson J., Kralstein J. Chronic constipation: a survey of the patient perspective // Aliment. Pharmacol. Ther. - 2007; 25: 599-608.
  17. Suares N., Ford A. Systematic review: the effects of fiber in the management of chronic idiopathic constipation // Aliment. Pharmacol. Ther. -2011; 33: 895-901.
  18. Muller-Lissner S., Kamm M., Scarpignato C. et al. Myths and misconceptions about chronic constipation // Am. J. Gastroenterol. - 2005; 100: 232-42.
  19. Dukas L., Willett W., Giovannucci E. Association between physical activity, fiber intake, and other lifestyle variables and constipation in a study of women // Am. J. Gastroenterol. - 2003; 98: 1790-6.
  20. Liu L. Chronic constipation: current treatment options // Can. J. Gastroenterol. - 2011; 25 (Suppl. B): 22-8.
  21. Corazziari E., Badiali D., Bazzocchi G. et al. Longterm efficacy, safety, and tolerabilitity of low daily doses of isosmotic polyethylene glycol electrolyte balanced solution (PMF-100) in the treatment of functional chronic constipation // Gut. - 2000; 46: 522-6.
  22. DiPalma J., DeRidder P., Orlando R. et al. A randomized, placebo-controlled, multicenter study of the safety and efficacy of a new polyethylene glycollaxative // Am. J. Gastroenterol. - 2000; 95: 446-50.
  23. Cinca R., Chera D., Gruss H. et al. Randomised clinical trial: macrogol/PEG 3350+electrolytes versus prucalopride in the treatment of chronic constipation - a comparison in a controlled environment // Aliment. Pharmacol. Ther. - 2013; 37 (9): 876-86.
  24. Corazziari E., Badiali D., Bazzocchi G. et al. Long term efficacy, safety, and tolerabilitity of low daily doses of isosmotic polyethylene glycol electrolyte balanced solution (PMF-100) in the treatment of functional chronic constipation // Gut. - 2000; 46: 522-6.
  25. Treepongkaruna S., Simakachorn N., Pienvichit P. et al. A randomised, double-blind study of polyethylene glycol 4000 and lactulose in the treatment of constipation in children // BMC Pediatr. - 2014; 14 (1): 153.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2016 Russkiy Vrach Publishing House

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies