THE MECHANISM OF THYROID HORMONE ACTION ON CHOLESTEROL METABOLISM
- Authors: Popova E.1, Tinkov A.1,2, Yakubovskaya A.1, Nikonorov A.1
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Affiliations:
- Orenburg State Medical University
- P.G. Demidov Yaroslavl State University
- Issue: Vol 28, No 5 (2017)
- Pages: 66-69
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/116970
- ID: 116970
Cite item
Abstract
The paper describes the main mechanisms of thyroid hormone actions on cholesterol metabolism and indicates the possible causes of dyslipidemia in patients with hypothyroidism.
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About the authors
E. Popova
Orenburg State Medical University
Email: elizbeth_p@bk.ru
Candidate of Medical Sciences
A. Tinkov
Orenburg State Medical University; P.G. Demidov Yaroslavl State UniversityCandidate of Medical Sciences
A. Yakubovskaya
Orenburg State Medical University
A. Nikonorov
Orenburg State Medical UniversityProfessor MD
References
- Rizos C., Elisaf M., Liberopoulos E. Effects of Thyroid Dysfunction on Lipid Profile // Open Cardiovasc. Med. J. - 2011; 5: 76-84.
- Mullur R., Liu Y., Brent G. Thyroid hormone regulation of metabolism // Rhysiol. Rev. - 2014; 94: 355-82.
- Cheng S., Leonard J., Davis Р. Molecular asрects of thyroid hormone actions // Endocr. Rev. - 2010; 31 (2): 139-70.
- Liu Y., Brent G. Thyroid hormone crosstalk with nuclear signaling in metabolic regulation // Trends Endocrinol. Metab. - 2010; 21: 166-73.
- Considine R. Thyroid hormone, Synthesis, Secretion and Metabolism. Medical physiology: Principles for Clinical Medicine. Fourth Edition, edited by R. Rhoades, D. Bell: Wolters Kluwer / Lippincott Williams and Wilkins, 2013; 626 p.
- Di Cosmo C., Liao X., Dumitrescu A. et al. Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion // J. Clin. Invest. - 2010; 120 (9): 3377-88.
- Mayerl S., Visser T., Darras V. et al. Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain // Endocrinology. - 2012; 153 (3): 1528-37.
- Gereben B., Zavacki A., Ribich S. et al. Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling // Endocr. Rev. - 2008; 29 (7): 898-938.
- Watanabe M., Houten S., Mataki C. et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation // Nature. - 2006; 439: 484-9.
- Leiria L., Dora J., Wajner S. et al. The rs225017 Polymorphism in the 3'UTR of the Human DIO2 Gene Is Associated with Increased Insulin Resistance // PLoS One. - 2014; 9 (8): e103960. doi: 10.1371/journal.pone.0103960.
- Simonides W., Mulcahey M., Redout E. et al. Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats // J. Clin. Invest. - 2008; 118: 975-83.
- Brent G. Mechanism of thyroid hormone action // J. Clin. Invest. - 2012; 122 (9): 3035-43.
- Semenza G. Defining the role of hypoxia-inducible factor 1 in cancer biology andtherapeutics // Oncogene. - 2010; 29: 625-34.
- Ruderman N., Carling D., Prentki M. et al. AMPK, insulin resistance, and themetabolic syndrome // J. Clin. Invest. - 2013; 123: 2764-71.
- Faure P., Oziol L., Artur Y. et al. Thyroid hormone (T3) and its acetic derivative (TA3) protect low-density lipoproteins from oxidation by different mechanisms // Biochimie. - 2004; 86: 411-8.
- Duntas L. Thyroid disease and lipids // Thyroid. - 2002; 2 (4): 287-93.
- Mushtaq S., Sheikh I., Rashid T. et al. Dyslipidemia in Thyroid Disorders // Indo Am. J. Pharmac. Res. - 2015; 5 (11): 3439-43.
- Kahaly G. Cardiovascular and Atherogenic Aspects of Subclinical Hypothyroidism // Thyroid. - 2000; 10 (8): 665-79.
- Diez J., Iglesias P. Serum cholesterol and triglyceride levels in diabetic patients with subclinical hypothyroidism // Orig. Res. Ar. Endocrinologia y Nutriciön (English Edition). - 2014; 61 (8): 419-25.