Central pontine myelinolysis
- Authors: Damulin I.1,2, Strutsenko A.3, Bychenko V.4
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Affiliations:
- I.M. Sechenov First Moscow State Medical University (Sechenov University)
- Central Research Institute of Gastroenterology, Moscow Clinical Research and Practical Center
- Peoples’ Friendship University of Russia
- Acad. V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology
- Issue: Vol 29, No 1 (2018)
- Pages: 29-32
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/117034
- DOI: https://doi.org/10.29296/25877305-2018-01-07
- ID: 117034
Cite item
Abstract
The paper considers the etiology, pathogenesis, clinical features, treatment, and prognosis of central pontine myelinolysis (CPM). It described a case of CPM arising in eating disorders, regular alcohol consumption, and uncontrolled use of diuretics, which cause electrolyte disturbances.
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About the authors
I. Damulin
I.M. Sechenov First Moscow State Medical University (Sechenov University); Central Research Institute of Gastroenterology, Moscow Clinical Research and Practical CenterProfessor
A. Strutsenko
Peoples’ Friendship University of RussiaCandidate of Medical Sciences
V. Bychenko
Acad. V.I. Kulakov Research Center of Obstetrics, Gynecology, and PerinatologyCandidate of Medical Sciences
References
- Martin R. Central pontine and extrapontine myelinolysis: the osmotic demyelination syndromes // J. Neurol., Neurosurg. Psychiatry. - 2004; 75 (Suppl. III): 22-8. doi: 10.1136/jnnp.2004.045906.
- Aoki R., Morimoto T., Takahashi Y. et al. Extrapontine myelinolysis associated with severe hypernatremia in infancy // Pediatr. Intern. - 2016; 58 (9): 936-9. doi: 10.1111/ped.13042.
- Mastrangelo S., Arlotta A., Cefalo M. et al. Central pontine and extrapontine myelinolysis in a pediatric patient following rapid correction of hypernatremia // Neuropediatrics. - 2009; 40 (03): 144-7. doi: 10.1055/s-0029-1243173.
- Alleman A. Osmotic demyelination syndrome: central pontine myelinolysis and extrapontine myelinolysis // Semin. Ultrasound, CT MRI. - 2014; 35 (2): 153-9. doi: 10.1053/j.sult.2013.09.009.
- Chang K., Lee I.-H., Kim G. et al. Plasma exchange successfully treats central pontine myelinolysis after acute hypernatremia from intravenous sodium bicarbonate therapy // BMC Nephrology. - 2014; 15: 56. doi: 10.1186/1471-236915-56.
- Shah M., Adrogue H., Mandayam S. Osmotic demyelination from iatrogenic hypernatremia // Am. J. Kidney Dis. - 2016; 67 (5): A98. DOI: 10.1053/j. ajkd.2016.03.324.
- Varanda S., Costa S., Carvalho R. et al. Central pontine myelinolysis caused by hypernatremia // J. Neurol. Sci. - 2016; 370: 274-6. DOI: 10.1016/j. jns.2016.10.001.
- Ashrafian H., Davey P. A review of the cases of central pontine myelinolysis: yet another apoptotic illness? // Eur. J. Neurol. - 2001; 8: 103-9. doi: 10.1046/j.1468-1331.2001.00176.x.
- Chu K., Kang D.-W., Ko S.-B. et al. Diffusion-weighted MR findings of central pontine and extrapontine myelinolysis // Acta Neurologica Scandinavica. - 2001; 104: 385-8. doi: 10.1034/j.1600-0404.2001.00096.x.
- Grimaldi D., Cavalleri F., Vallone S. et al. Plasmapheresis improves the outcome of central pontine myelinolysis // J. Neurol. - 2005; 252: 734-5. doi: 10.1007/s00415-005-0738-7.
- Laureno R. Disorders of water and sodium balance. /In: Neurological Therapeutics Principles and Practice. Ed. J. Noseworthy. Second edition / Adingdon etc.: Informa Healthcare, 2006; Vol. 2., Ch. 122: p. 1454-5.
- Koussa S., Nasnas R. Catatonia and Parkinsonism due to extrapontine myelinolysis following rapid correction of hyponatremia. A case report // J. Neurol. - 2003; 250: 103-5. doi: 10.1007/s00415-003-0916-4.
- Shamim A., Siddiqui B., Josephs K. The corticobasal syndrome triggered by central pontine myelinolysis // Eur. J. Neurol. - 2006; 13: 82-4. doi: 10.1111/j.1468-1331.2006.01221.x.
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