Vol 29, No 1 (2018)

The paper considers the possibilities of using generic counterparts of their brand-name drugs in outpatients who have experienced myocardial infarction. Assessing the relationship between higher mental functions and blood pressure (BP), it is necessary to recognize the need for a rational approach to a stepwise BP reduction.

Male patients with glomerulonephritis at the predialysis stage of chronic kidney disease show a predominance of concentric left ventricular hypertrophy that is associated with the development of clinically significant cardiac arrhythmias. Whereas female patients with chronic glomerulonephritis have a lower glomerular filtration rate, anemia, a higher frequency of eccentric left ventricular hypertrophy and supraventricular ectopic activity.

A total of 721 patients aged 19 to 91 years were examined and treated in a multicenter randomized prospective study. The use of psyllium (Mucofalk) in multitargeted therapy was justified in patients with hyperlipidemia, metabolic syndrome, and constipation. Mucofalk was proven to have a lipid-lowering effect in all patient groups; it was demonstrated that the drug could be co-administered with statins for synergistic action in patients at high and very high risk for cardiovascular diseases. Stool was normalized in the majority of patients long treated with Mucofalk. Drug discontinuation was not required in any patient. Twenty-four Mucofalk therapy reduced body mass index by an average of 4.759.80% without substantial dietary restrictions in the patients.

The paper considers the etiology, pathogenesis, clinical features, treatment, and prognosis of central pontine myelinolysis (CPM). It described a case of CPM arising in eating disorders, regular alcohol consumption, and uncontrolled use of diuretics, which cause electrolyte disturbances.

The paper gives the results of investigations, which suggest that young women with estro-gen deficiency and hypertension show a certain association between body mass index (BMI) and 24-hour monitoring readings, such as an elevation in systolic and diastolic blood pressure (BP) at different times of the day, the high magnitude and rate of morning surge in BP with a higher pres-sure-induced load as BMI increases. The high correlation of BMI and the power of LF waves that characterize the sympathetic portion of the spectrum may be regarded as evidence for a pathoge-netic relationship between BMI and the degree of sympathetic nervous system activity.

Structural and functional changes in the cardiovascular system, lipid spectrum and indicators were investigated to determine risk factors for complications in kidney recipients in different periods after transplantation.

The paper considers the practicability of computer-aided calculation of glomerular filtration rate in diabetic patients, by applying the computer program “Chronic_ Kidney_Disease_Diagnostics” that makes it possible to diagnose chronic kidney disease at an early preclinical stage.

The paper gives the results of treatment using the methods of manual therapy and pharmacopuncture with bioregulatory drugs in pregnant women with vertebrogenic pain syndromes.

Autonomic regulation of the cardiovascular system has been assessed in 192 boys of pre-draft age with various subclinical forms of cardiovascular diseases and in 50 children of a control group. The findings suggest that sympathicotonia is predominant in the examinees of the study group.

The paper presents the results of gonarthrosis treatment using a traditional basic treatment complex, para-articular ozone administration, and cycle Osteomed intake.

Arthroplasty is the only current method against pain and movement stiffness in patients with knee osteoarthritis (KOA). The paper describes the features of knee arthroplasty in patients with rheumatoid arthritis.

Bioregulatory medications normalize metabolic processes, activate and regulate the immune system, and contribute to the natural elimination of excess and harmful substances.

The paper describes a rare case of ANCA-negative Wegener's granulomatosis with a severe, fulminant course, which is manifested by primary ENT involvement.