A diagnostic and treatment algorithm and prognosis of surgical treatment for pancreatic insulin-producing tumors


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The clinical, laboratory, and topical diagnosis of insulin-producing neuroendocrine tumors of the pancreas can be difficult, and their surgical treatment is accompanied by a relatively high rate of complications and mortality, which, along with a favorable prognosis of the disease, makes it necessary to search for alternative approaches to diagnosis and treatment.

Full Text

Restricted Access

About the authors

D. Lezhinsky

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: dlezinski@gmail.com

A. Egorov

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: dlezinski@gmail.com
MD

I. Vasilyev

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: dlezinski@gmail.com
Candidate of Medical Sciences

S. Kondrashin

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: dlezinski@gmail.com
MD

E. Fominykh

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: dlezinski@gmail.com
Candidate of Medical Sciences

G. Musaev

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: dlezinski@gmail.com
Professor

V. Parnova

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: dlezinski@gmail.com
Candidate of Medical Sciences

I. Ivashov

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: dlezinski@gmail.com

A. Mironova

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: dlezinski@gmail.com

N. Abdulkhaklmov

University Clinical Hospital One, I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: dlezinski@gmail.com

References

  1. Metz D., Jensen R. Gastrointestinal neuroendocrine tumors: Pancreatic endocrine tumors // Gastroenterology. - 2008; 135: 1469-92.
  2. Vanderveen K., Grant C. Insulinoma // CancerTreat. Res. - 2010; 153: 235-52.
  3. de Herder W., Niederle B., Scoazec J. et al. Well-Differentiated Pancreatic Tumor/Carcinoma: Insulinoma // ENETS Guidelines. Neuroendocrinology. - 2006; 84: 183-8.
  4. Mathur A., Gorden P., Libutti S. Insulinoma // Surg. Clin. North Am. - 2009; 89: 1105-21.
  5. Дедов И.И., Мельниченко Г.А., Фадеев В.В. Эндокринология. 2-е изд. / М., 2009; 432 с.
  6. Kulke M., Anthony L., Bushnell D. et al. NANETS Treatment Guidelines: welldifferentiated neuroendocrine tumors of the stomach and pancreas // Pancreas. - 2010; 39: 735-52.
  7. Guettier J., Gorden P. Insulin secretion and insulin-producing tumors // Expert Rev. Endocrinol. Metab. - 2010; 5: 217-27.
  8. Морозов Ю.А. Сравнительная оценка информативности различных дооперационных методов топической диагностики при инсулиномах. Автореф. дис.. канд. мед. наук. М., 1998; 24 с.
  9. Егоров А.В., Мусаев Г.Х., Фоминых Е.В. и др. Эволюция алгоритма топической диагностики гормонально-активных нейроэндокринных опухолей поджелудочной железы // Анн. хир. гепатол. - 2016; 1: 21.
  10. Gouya Н., Vignaux O., Augui J., et al. CT, Endoscopic Sonography, and a Combined Protocol for Preoperative Evaluation of Pancreatic Insulinomas // Am. J. Roentgenol. - 2003; 181: 987-92.
  11. Ardengh J., Valiati L., Geocze S. Identification of insulinomas by endoscopic ultrasonography // Rev. Assoc. Med. Bras. - 2004; 50 (2): 167-71.
  12. Zhu L., Xue H., Sun Z. et al. Prospective comparison of biphasic contrast-enhanced CT, volume perfusion CT, and 3 Tesla MRI with diffusion-weighted imaging for insulinoma detection // J. Mang. Reson. Imaging. - 2017; 46 (6): 1648-55. doi: 10.1002/jmri.25709.
  13. Baba Y., Miyazono N., Nakajo M. et al. Localization of insulinomas: Comparison of conventional arterial stimulation with venous sampling (ASVS) and superselective ASVS // Acta Radiol. - 2000; 41: 172-7.
  14. Akerstrom G., Hellman P. Surgery on neuroendocrine tumours // Best Pract. Res. Clin. Endocrinol. Metab. - 2007; 21: 87-109.
  15. Goh B., Ooi L., Cheow P. et al. Accurate preoperative localization of insulinomas avoids the need for blind resection and reoperation: analysis of a single institution experience with 17 surgically treated tumors over 19 years // J. Gastrointest. Surg. - 2009; 13 (6): 10717.
  16. Machado M., da Cunha J., Jukemura J. et al. Insulinoma: diagnostic strategies and surgical treatment. A 22-year experience // Hepatogastroenterology. - 2001; 48 (39): 854-8.
  17. Fendrich V., Waldmann J., Bartsch D. Surgical management of pancreatic endocrine tumors // Nat. Rev. Clin. Oncol. - 2009; 6: 419-28.
  18. Espana-Gomez M., Velazquez-Fernandez D., Bezaury P. Pancreatic insulinoma: a surgical experience // World J. Surg. - 2009; 33: 1966-70.
  19. Shan-yu Qin, Xiu-ping Lu, Hai-xing Jiang. EUS-Guided Ethanol Ablation of Insulinomas Case Series and Literature Review // Medicine (Baltimore). - 2014; 93 (14): 85.
  20. Черноусов А.Ф., Егоров А.В., Мусаев Г.Х. и и др. Микроволновая абляция инсулином // Анналы хирургической гепатологии. - 2016; 21 (4): 35-40.
  21. Varshney S., Johnson C. Neuroendocrine tumors of the pancreas // Indian J. Gastroenterol. - 2000; 19 (4): 181-3.
  22. Krieger A., Smirniv A., Berelavichus S. et al. Organic hyperinsulunism: radiological diagnostics and surgical treatment // Ann: Khirurgiia (Mosk). - 2016; 6: 14-29.
  23. Crippa S., Zerbi A., Boninseqna L. et al. Surgical management of insulinomas: short and long-term outcomes after enucleations and pancreatic resections // Arch. Surg. - 2012; 147 (3): 261-6. DOI: 10.1001/ archsurg.2011.1843.
  24. Menegaux F., Schmitt G., Mercadier M. Pancreatic insulinomas // Am. J. Surg. - 1993; 165 (2): 243-8.
  25. Кузин Н.М., Егоров А.В. Нейроэндокринные опухоли поджелудочной железы. Руководство / М.: Медицина, 2001; 208 с.
  26. Machado M., da Cunha J., Jukemura J. et al. Insulinoma: diagnostic strategies and surgical treatment. A 22-year experience // Hepatogastroenterology. - 2001; 48 (39): 854-8.
  27. Franz R., Penzhorn H. Is total gastrec- tomy still a viable option in the manage- ment of patients with the Zollinger-Ellison syndrome? // Afr. J. Surg. -2007; 45: 58-60.
  28. Кривко А.А. Инсулинома: отдаленные результаты лечения и разработка современного протокола топической диагностики и реабилитации. Дис.. канд. мед. наук. М., 2015.
  29. Chung J., Choi S., Jo S. et al. Localization and surgical treatment of the pancreatic insulinomas // ANZ J. Surg. - 2006; 76 (12): 1051-5.
  30. Wei J., Liu X., Wu J. et al. Diagnosis and surgical management of insulinomas in 33 consecutive patients at a single institution // Langenbecks Arch. Surg. - 2016; 401 (7): 1019-25.
  31. Phan G., Yeo C., Hruban R. et al. Surgical experience with pancreatic and peripancreatic neuroendocrine tumors: review of 125 patients // J. Gastrointest. Surg. - 1998; 2 (5): 472-82.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies