Atopic dermatitis: psychosomatic aspects


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Abstract

The paper considers the presumed mechanisms of the etiology and pathogenesis of a common skin disease, such as atopic dermatitis (AD), from the point of view of psychosomatic theories and models in modern medicine. It analyzes the literature data suggesting that the peptidergic and immune systems are actively involved in the development of key symptoms of the disease. The systems of monoamine neurotransmitters (dopamine, noradrenaline, and serotonin) participating in the development and functioning of all mental processes (emotions, thinking, perception, etc.) were found to also play an important role in the pathogenesis of AD. There are examples of successfully using drugs from the groups of neuroleptics, antidepressants, tranquilizers in AT.

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About the authors

N. Potekaev

N.I. Pirogov Russian National Research Medical University; Moscow Research-and-Practical Center of Dermatovenereology and Cosmetology, Moscow Healthcare Department

Email: marykor@bk.ru

I. Danilin

Peoples’ Friendship University of Russia

Email: marykor@bk.ru

I. Korsunskaya

Moscow Research-and-Practical Center of Dermatovenereology and Cosmetology, Moscow Healthcare Department; Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences

Email: marykor@bk.ru

A. Kostolevskaya

Moscow Research-and-Practical Center of Dermatovenereology and Cosmetology, Moscow Healthcare Department

Email: marykor@bk.ru

Z. Nevozinskaya

Moscow Research-and-Practical Center of Dermatovenereology and Cosmetology, Moscow Healthcare Department

Email: marykor@bk.ru

M. Artemyeva

Peoples’ Friendship University of Russia

Email: marykor@bk.ru

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