Polypragmasia in ophthalmic practice


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Abstract

The paper provides a discussion of the clinical case of female patient P. aged 70 years, who applied for examination to the Advisory Department, Eye Hospital, with the previously verified diagnosis of grade 1a open-angle glaucoma, early cataract, and mild hypermetropia. During instillations of the local formulation of a ß-adrenoblocker and an а-adrenomimetic in combination with paroxetine (an antidepressant of the selective serotonin reuptake inhibitor group), the patient developed weakness, hypotension, and bradycardia (blood pressure, 100/60 mm Hg; heart rate, 58 beats/min). In this case, there was a serious adverse reaction that was significantly associated with the adverse drug interaction according to the Horn-Hansten scale).

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About the authors

L. Moshetova

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Professor, MD, Academician of the Russian Academy of Sciences

M. Soshina

Russian Medical Academy of Continuing Professional Education

D. Sychev

Russian Medical Academy of Continuing Professional Education

Professor, MD, Corresponding Member of the Russian Academy of Sciences

K. Turkina

Russian Medical Academy of Continuing Professional Education

Candidate of Medical Sciences

A. Lopareva

I.M. Sechenov First Moscow State Medical University (Sechenov University)

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