Detection rates of anti-cyclic citrullinated peptide (anti-CCP and anti-MCV) antibodies in patients with juvenile idiopathic arthritis and clinical characteristics of seropositive patients


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Abstract

The paper provides data on the detection rates of antibodies against anti-cyclic citrullinated peptide (anti-CCP) and modified citrullinated vimentin (anti-MCV) in children with juvenile idiopathic arthritis and gives the clinical characteristics of seropositive patients. By and large, anti-CCP antibodies were found in 25.4% of cases. At the time of examination more than 70% of patients seropositive for anti-CCP and anti-MCV developed symmetric polyarthritis, regardless of the type of disease onset.

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About the authors

T. Shilova

South Ural State Medical University

Email: tanya920477@mail.ru
Candidate of Medical Sciences Chelyabinsk

A. Pishchalnikov

South Ural State Medical University

Email: tanya920477@mail.ru
MD Chelyabinsk

D. Volosnikov

South Ural State Medical University

Email: tanya920477@mail.ru
MD Chelyabinsk

E. Serebryakova

South Ural State Medical University

Email: tanya920477@mail.ru
Candidate of Medical Sciences Chelyabinsk

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