Mechanisms of neuroplasticity in patients with diabetes mellitus


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Abstract

The paper presents the issues of neuroplasticity in patients with diabetes mellitus and in experimental models, as well as the effect of insulin, the variability of glycemia, and the level of brain-derived neurotrophic factor on plasticity.

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About the authors

M. Matveeva

Siberian State Medical University

Email: matveeva.mariia@yandex.ru
Candidate of Medical Sciences

Yu. Samoilova

Siberian State Medical University

N. Zhukova

Siberian State Medical University

M. Rotkank

Siberian State Medical University

O. Leiman

Siberian State Medical University

References

  1. Niеto-Sampedro M., Nieto-Dias M. Neuralplasticity: changes with age // J. Neural. Transm. - 2005; 112: 3-27.
  2. Manto M., Oulad ben Taib N., Luft A. Modulation of excitability as an early change leading to structural adaptation in the motor cortex // J. Neuro. Sci. Res. -2006; 83 (2): 177-80.
  3. IDF. Diabetes Atlas. 7th ed. Available at: http://www.diabetesatlas.org/ Accessed July 11, 2017.
  4. Гуляева Н.В. Молекулярные механизмы нейропластичности: расширяющаяся вселенная // Биохимия. - 2017; 82 (3): 365-71.
  5. Салмина А.Б., Яузина Н.А., Кувачева Н.В. и др. Инсулин и инсулинорезистентность: новые молекулы-маркеры для диагностики и терапии для заболеваний центральной неврной системы // Бюл. сиб. медицины. - 2013; 12 (5): 104-18.
  6. Claudia A., Gerardo G., Lowrence R. et al. Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity // Diabetes. - 2015; 64: 3927-36. doi: 10.2337/db15-0596.
  7. MatsunagaY., Negishi T., Hatakeyama A. et al. Impairment of synaptic development in the hippocampus of diabetic Goto-Kakizaki rats // Int. J. Dev. Neurosci. - 2016; 53: 58-67. doi: 10.1016/j.ijdevneu.2016.07.004.
  8. Qu Z., Jiao Z., Sun X. et al. Effects of streptozotocin-induced diabetes on tau phosphorylation in the rat brain // Brain Res. - 2011; 1383: 300-6.
  9. Sun L. Hippocampal IGF-1 expression, neurogenesis and slowed aging: clues to longevity from mutant mice // Age. - 2006; 28 (2): 181-9. DOI: 10.1007/ s11357-006-9009-5.
  10. Brooker G., Kalloniatis M., Russo V. et al. Endogenous IGF-1 regulates the neuronal differentiation of adultstemcells // J. Neurosci. Res. - 2000; 59 (3): 33241. doi: 10.1002/(SICI)1097-4547(20000201)59:3<332::AID-JNR6>3.0.CO;2-2.
  11. Chell J., Brand A. Nutrition-responsive glia control exit of neural stem cells from quiescence // Cell. - 2010; 143 (7): 1161-73. doi: 10.1016/j.cell.2010.12.007.
  12. Moreira T., Cebers G., Pickering C. et al. Diabetic Goto-Kakizaki rats display pronounced hyperglycemia and longer-lasting cognitive impairments following ischemia induced by cortical compression // Neuroscience. - 2007; 144: 1169-85.
  13. Simpson I., Appel N., Hokari M. et al. Blood-brain barrier glucose transporter: effects of hypo- and hyperglycemia revisited // J. Neurochem. - 1999; 72: 238-47.
  14. Bree A., Puente E., Daphna-Iken D. et al. Diabetes increases brain damage caused by severe hypoglycemia // Am. J. Physiol. Endocrinol. Metab. - 2009; 297 (1): E194-E201. doi: 10.1152/ajpendo.91041.2008. PMCID: PMC2711670
  15. Martinez-Tellez R., Gomez-Villalobos M., Flores G. Alteration in dendritic morphology of cortical neurons in rats with diabetes mellitus induced by streptozotocin // Brain Res. - 2005; 1048: 108-15.
  16. Suh S., Hamby A., Swanson R. Hypoglycemia, brain energetics, and hypoglycemic neuronal death // Glia. - 2007; 55: 1280-6.
  17. Trudeau F., Gagnon S., Massicotte G. Hippocampal synapticplasticity and glutamate receptor regulation: influences of diabetes mellitus // Eur. J. Pharmacol. -2004; 490 (1-3): 177-86.
  18. Li N., Young M., Bailey C. et al. NMDA and AMPA glutamate receptor subtypes in the thoracic spinal cord in lean and obese-diabetic ob/ob mice // Brain Res. - 1999; 849 (1-2): 34-44.
  19. Thomas J., Garg M., Smith D. Altered expression of histone and synaptic plasticity associated genes in the hippocampus of streptozotocin-induced diabetic mice // Metab. Brain Dis. - 2013; 28 (4): 613-8. doi: 10.1007/s11011-013-9418-y.
  20. Kodl C., Seaquist E. Cognitive dysfunction and diabetes mellitus // Endocrine Reviews. - 2008; 29 (4): 494-511. doi: 10.1210/er.2007-0034.

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