Possibilities of diagnosis, treatment and prevention of functional diseases of the gallbladder and sphincter of Oddi

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Abstract

The detection of functional disorders of the gastrointestinal tract is statistically reliable in almost 50% of patients, of which about 15% are biliary disorders of the adult population. The gallbladder accounts for more than 12.5% of all biliary disorders, which proves the significant contribution of this pathology to the overall statistics of gastrointestinal morbidity.

Currently, the treatment, differential diagnosis of this pathology is associated with a number of difficulties, and first of all this is due to various anatomical features of the gallbladder and excretory ducts. The diagnosis of this pathology, especially the motility of the gallbladder, requires the use of modern medications, such as Hofitol, which provides a pronounced hepatoprotective effect in the form of normalization of enzyme activity, bilirubin levels, lipid composition, effectively eliminates the main clinical manifestations of bile sludge, dysfunction of the gastrointestinal tract, restores its motor evacuation function and is well tolerated by patients.

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About the authors

P. V. Seliverstov

S.M. Kirov Military Medical Academy

Author for correspondence.
Email: seliverstov-pv@yandex.ru
ORCID iD: 0000-0001-5623-4226

Candidate of Medical Sciences, Associate Professor

Russian Federation, Saint Petersburg

V. P. Kutsenko

Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia

Email: seliverstov-pv@yandex.ru
ORCID iD: 0000-0001-9755-1906

Candidate of Medical Sciences

Russian Federation, Saint Petersburg

E. S. Ivanyuk

Военно-медицинской академии им. С.М. Кирова Минобороны России

Email: seliverstov-pv@yandex.ru
ORCID iD: 0000-0002-2785-6699

Candidate of Medical Sciences

Russian Federation, Saint Petersburg

Yu. A. Kravchuk

S.M. Kirov Military Medical Academy

Email: seliverstov-pv@yandex.ru
ORCID iD: 0000-0001-8347-0531

MD, Professor

Russian Federation, Saint Petersburg

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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig.1. Structure of the biliary system [5]

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3. Fig. 2. Assessment of biliary pain in patients without organic pathology of the gallbladder [9]

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4. Fig. 3. Variants of inflections of the gallbladder (neck, body, bottom)

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5. Fig. 4. Variants of the structure of the cystic duct

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6. Fig. 5. Structure of the gallbladder: 1 – duct of Luschka; 2 – intrahepatic duct; 3 – gallbladder muscle; 4 – Rokitansky–Aschoff sinuses

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7. Fig. 6. Physiological effects of the use of Chophytol

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8. Fig. 7. Dynamics of bile sludge on the background of Chophytol therapy according to ultrasound data: а – before treatment; б – 1 month after treatment

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