The function of right cardiac chambers in patients with asthma according to doppler echocardiography

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Abstract

Objective. To determine the functional state of right cardiac chambers in patients with asthma of varying severity according to Doppler echocardiography.

Subjects and methods. Cardiopulmonary hemodynamics was assessed in 56 asthmatic patients, by using ultrasound. The examinees were divided into 3 groups by the severity of the disease.

Results. With an increase in the severity of asthma, diastolic dysfunction of the right ventricle (RV) progressed with the development of its dysfunction that further plays a dominant role in developing chronic heart failure. As diastolic dysfunction of the RV progressed in the asthmatic patients, there was an increase in the contractile activity of the right atrium (RA) simultaneously with a decrease in the Е/А ratio.

Conclusion. In asthmatic patients, diastolic dysfunction in the right cardiac chambers frequently precedes systolic dysfunction, which manifests itself in a change in the ratio of various phases of RV filling. During RV diastolic dysfunction, there is a relative increase in the contractility of RA.

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About the authors

O. N. Titova

Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia

Email: dissovspbgmu02@mail.ru

Professor, MD

Russian Federation, Saint Petersburg

N. A. Kuzubova

Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia

Email: dissovspbgmu02@mail.ru

MD

Russian Federation, Saint Petersburg

A. L. Aleksandrov

Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia

Email: dissovspbgmu02@mail.ru

Professor, MD

Russian Federation, Saint Petersburg

V. Perlei

Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia

Email: dissovspbgmu02@mail.ru

Professor, MD

Russian Federation, Saint Petersburg

A. Yu. Gichkin

Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia

Author for correspondence.
Email: dissovspbgmu02@mail.ru

Candidate of Medical Sciences

Russian Federation, Saint Petersburg

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