Clinical and functional features and quality of life in various phenotypes of occupational asthma

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Abstract

An analysis of clinical symptoms, indicators of external respiration and quality of life (QoL) of patients with various phenotypes of occupational asthma (OA) was carried out (according to the analysis of the results of the MOS SF-36 questionnaire). For all OA phenotypes, there was a decrease in forced expiratory parameters, as well as indices of both mental and physical health compared to the control group (conditionally healthy) (p<0.001). Significantly low quality of life indicators were detected in patients with the “OA with metabolic syndrome” phenotype on the scales of physical functioning, general health, vital activity, social functioning and role functioning due to emotional state. In the group of patients with the non-allergic phenotype of OA, higher quality of life indicators were observed compared to other phenotypes of the disease.

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About the authors

S. Babanov

Samara State Medical University, Ministry of Health of Russia

Author for correspondence.
Email: s.a.babanov@mail.ru
ORCID iD: 0000-0002-1667-737X

MD, Professor 

Russian Federation, Samara

L. Strizhakov

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: s.a.babanov@mail.ru
ORCID iD: 0000-0002-2291-6453

MD, Professor 

Russian Federation, Moscow

A. Baikova

Samara State Medical University, Ministry of Health of Russia

Email: s.a.babanov@mail.ru
ORCID iD: 0000-0003-3438-6602

Candidate of Medical Sciences

Russian Federation, Samara

A. Melentev

F.F. Erisman Federal Scientific Center of Hygiene

Email: s.a.babanov@mail.ru
ORCID iD: 0000-0002-1074-0841

Candidate of Medical Sciences

Russian Federation, Mytishchi

A. Agarkova

Samara State Medical University, Ministry of Health of Russia

Email: s.a.babanov@mail.ru
ORCID iD: 0000-0002-4065-5875
Russian Federation, Samara

V. Lotkov

Samara State Medical University, Ministry of Health of Russia

Email: s.a.babanov@mail.ru
ORCID iD: 0000-0002-3995-6988

MD, Professor

Russian Federation, Samara

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