Factors of early neonatal maladaptation of late preterm infants

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Abstract

Late preterm infants are more susceptible to various unfavorable factors than preterm infants. The leading place in the structure of morbidity, as well as the formation of long-term unfavorable outcomes in this group of children is occupied by respiratory disorders, impaired or delayed neurodevelopment. In order to study in detail the pathological conditions leading to adaptation disorders, we retrospectively analyzed the data of developmental histories of late premature infants and delivery histories. The relationship between placental abnormalities, including fetal growth and developmental delays, fetal conception, history of pregnancy termination, low birth weight, age of the woman in labor and increased need for respiratory support, as well as clinical manifestations of cerebral ischemia in newborns at 34 0/7–36 6/7 weeks gestation was revealed.

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About the authors

N. I. Panina

N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia; Voronezh City Clinical Emergency Hospital No.10, Maternity hospital «Electronika»

Author for correspondence.
Email: ivanadjushkapanina@yandex.ru
ORCID iD: 0000-0002-8499-8079
Russian Federation, Voronezh; Voronezh

L. I. Ippolitova

N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia; Voronezh Regional Clinical Hospital No.1, Perinatal Center

Email: ivanadjushkapanina@yandex.ru
ORCID iD: 0000-0001-7076-0484

MD

Russian Federation, Voronezh; Voronezh

E. Ya. Kaledina

N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia; Voronezh City Clinical Emergency Hospital No.10, Maternity hospital «Electronika»

Email: ivanadjushkapanina@yandex.ru
ORCID iD: 0000-0001-9459-6789

Candidate of Medical Sciences

Russian Federation, Voronezh; Voronezh

M. I. Kogutnitskaya

N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia

Email: ivanadjushkapanina@yandex.ru
ORCID iD: 0000-0002-4336-6235

Candidate of Medical Sciences

Russian Federation, Voronezh

N. N. Korotaeva

N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia; Voronezh Regional Clinical Hospital No.1, Perinatal Center

Email: ivanadjushkapanina@yandex.ru
ORCID iD: 0000-0001-5859-7717

Candidate of Medical Sciences

Russian Federation, Voronezh; Voronezh

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Supplementary files

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2. Fig. 1. Analysis of the «Pregnancy Count» indicator as a function of the «Baby's Need For Ventilator» indicator

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3. Fig. 2. ROC-curve characterizing the dependence of the probability of the indicator «Baby's Need For Ventilator» on the indicator «Pregnancy Count»

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4. Fig. 3. ROC-curve characterizing the dependence of the probability of the indicator «Baby's Need For Ventilator» on the indicator «births by count»

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5. Fig. 4. Analysis of the indicator «Mother's Age» as a function of the indicator «Baby's Need For Ventilator»

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6. Fig. 5. ROC-curve characterizing the dependence of the probability of the indicator « Baby's Need For Ventilator » on the indicator «Mother's Age»

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7. Fig. 6. Analysis of the indicator «Mother's Age» depending on the indicator «Cerebral Ischemia II Degree»

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8. Fig. 7. ROC-curve characterizing the dependence of the probability of the indicator «Cerebral ischemia of the II degree» on the indicator «Mother's Age»

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