Databases of potential digital doubles of the software-modeling complex for predicting leading indicators of patients' condition

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In modern personalized medicine, there is a transition from the phenomenological description of clinical cases to the predictive modeling of individual patient trajectories. In this context, the concept of medical digital twins seems to be not so much a technological innovation as a qualitatively new epistemological tool that requires rethinking traditional approaches to the organization and structuring of medical data. In this regard, the fundamental challenge is not the very possibility of computational modeling of physiological processes, which is technically feasible in one way or another, but the formation of an adequate information infrastructure capable of ensuring the representativeness and validity of the source data for predictive algorithms. The methodology of forming databases of potential digital counterparts in medicine is currently under development. Our research has allowed us to develop an approach to the formation of a database of medical digital twins and formulate several fundamental provisions that determine the directions for further development of the information infrastructure for predicting the condition of patients based on them.

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作者简介

E. Minakov

A.F. Mozhaisky Military Aerospace Academy, Ministry of Defense of Russia

Email: seliverstov-pv@yandex.ru
SPIN 代码: 4819-0765

Professor, Doctor of Engineering Sciences

俄罗斯联邦, Saint Petersburg

V. Grinevich

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

Email: seliverstov-pv@yandex.ru
ORCID iD: 0000-0002-1095-8787
SPIN 代码: 1178-0242

Professor, MD

俄罗斯联邦, Saint Petersburg

E. Kryukov

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

Email: seliverstov-pv@yandex.ru
ORCID iD: 0000-0002-8396-1936
SPIN 代码: 3900-3441

Professor, Academician of the Russian Academy of Sciences, MD

俄罗斯联邦, Saint Petersburg

P. Seliverstov

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

编辑信件的主要联系方式.
Email: seliverstov-pv@yandex.ru
ORCID iD: 0000-0001-5623-4226
SPIN 代码: 6166-7005

Associate Professor, Candidate of Medical Sciences

俄罗斯联邦, Saint Petersburg

参考

  1. Vallée A. Digital twin for healthcare systems. Front Digit Health. 2023; 5: 1253050. doi: 10.3389/fdgth.2023.1253050
  2. Селиверстов П.В., Гриневич В.Б., Крюков Е.В. и др. Роль цифровых двойников в терапевтическом сопровождении пациентов. Врач. 2025; 36 (6): 13–9 [Seliverstov P., Grinevich V., Kryukov E. et al. The role of digital doubles in the therapeutic support of patients. Vrach. 2025; 36 (6): 13–9 (in Russ.)]. doi: 10.29296/25877305-2025-06-03
  3. Кобякова О.С., Стародубов В.И., Куракова Н.Г. и др. Цифровые двойники в здравоохранении: оценка технологических и практических перспектив. Вестник РАМН. 2021; 76 (5): 476–87 [Kobyakova O.S., Starodubov V.I., Kurakova N.G. et al. Digital Twins in Healthcare: an Assessment of Technological and Practical Prospects. Annals of the Russian Academy of Medical Sciences. 2021; 76 (5): 476–87 (in Russ.)]. doi: 10.15690/vramn1717
  4. Гриневич В.Б., Крюков Е.В., Минаков Е.П. и др. Концепция применения цифровых двойников для прогнозирования значений ведущих показателей состояния здоровья пациентов. Врач. 2025; 36 (9): 82–6 [Grinevich V., Kryukov E., Minakov E. et al. The concept of using digital twins to predict the values of leading indicators of patients' condition. Vrach. 2025; 36 (9): 83–6 (in Russ.)]. doi: 10.29296/25877305-2025-09-16
  5. Прохорова Н.Д., Лебедев Г.С., Прасолов М.С. и др. Применение цифровых двойников в здравоохранении. Менеджер здравоохранения. 2024; 11: 88–96 [Prokhorova N.D., Lebedev G.S., Prasolov M.S. et al. The use of digital twins in healthcare. The health care manager. 2024; 11: 88–96 (in Russ.)]. doi: 10.21045/1811-0185-2024-11-88-96
  6. Attaran M., Celik B.G. Digital twin: benefits, use cases, challenges, and opportunities. Decis Anal J. 2023; 6: 100165. doi: 10.1016/j.dajour.2023.100165
  7. Armeni P., Polat I., De Rossi L.M. et al. Digital twins in healthcare: is it the beginning of a new era of evidence-based medicine? A critical review. J Pers Med. 2022; 12: 1255. doi: 10.3390/jpm12081255
  8. Sun T., He X., Li Z. Digital twin in healthcare: recent updates and challenges. Digit Health. 2023; 9: 20552076221149651. doi: 10.1177/20552076221149651
  9. Sun T., He X., Song X. et al. The digital twin in medicine: a key to the future of healthcare? Front Med. 2022; 9: 907066. doi: 10.3389/fmed.2022.907066
  10. Haleem A., Javaid M., Pratap Singh R. et al. Exploring the revolution in healthcare systems through the applications of digital twin technology. Biomed Technol. 2023; 4: 28–38. doi: 10.1016/j.bmt.2023.02.001
  11. Garanin A.A., Aydumova O.Y., Kiselev A.R. Digital twins in healthcare administration: A systematic review on novel approaches to management and planning. Russian Open Medical Journal. 2025; 14: e0104. doi: 10.15275/rusomj.2025.0104
  12. Elkefi S., Asan O. Digital twins for managing health care systems: rapid literature review. J Med Internet Res. 2022; 24: e37641. doi: 10.2196/37641
  13. Денисов С.Г. Технологии сбора и обработки данных для создания цифровых двойников. Бюллетень инновационных технологий. 2023; 7 (2): 12–7 [Denisov S.G. Data collection and processing technologies for creating digital doubles. Bulletin of innovative technologies. 2023; 7 (2): 12–7 (in Russ.)].
  14. Михеев А.Е. Перспективы создания цифровых медицинских экосистем в России: цифровые двойники и другие технологии, проблемы и подходы. Менеджер здравоохранения. 2024; S: 4–32 [Mikheev A.E. Prospects of creating digital medical ecosystems in Russia: digital twins and other technologies, problems and approaches. The health care manager. 2024; S: 4–32 (in Russ.)]. doi: 10.21045/1811-0185-2024-S-4-32
  15. Архитектура экосистем [Электронный ресурс] [Ecosystem architecture [Electronic resource] (in Russ.)]. URL: https://habr.com/ru/companies/nspk/articles/532462/
  16. Баранов Л.И., Бушманов А.Ю., Васильев Е.В. и др. Цифровой двойник и цифровой профиль как основа сбора и анализа медицинских данных. Медицинская радиология и радиационная безопасность. 2025; 70 (4): 39–45 [Baranov L.I., Bushmanov A.Yu., Vasilev Е.V. et al. The Digital Twin and the Digital Profile as the Basis for the Collection and Analysis of Medical Data. Medical Radiology and Radiation Safety. 2025; 70 (4): 39–45 (in Russ.)]. doi: 10.33266/1024-6177-2025-70-4-39-45
  17. Михеев А.Е. Возможности, проблемы и перспективы информационных технологий в сфере клинической безопасности. Менеджер здравоохранения. 2023; S: 5–20 [Mikheev A.E. Opportunities, problems and prospects of information technologies in the field of clinical safety. The health care manager. 2023; S: 5–20 (in Russ.)]. doi: 10.21045/1811-0185-2023-S-5-20
  18. Александер М., Куслейка Р. Microsoft Excel 2019. Библия пользователя. Пер. с англ. СПб: ООО «Диалектика», 2019; 1136 с. [Alexander M., Kusleika R. Microsoft Excel 2019. Bible. Transl. from Engl. SPb: LLC «Dialectics», 2019; 1136 p. (in Russ.)].

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2. Fig. 1. Method of forming a database of potential digital twins

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3. Fig. 2. Structure of the software-modeling complex

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4. Fig. 3. Database form

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