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Vol 26, No 9 (2015)

Articles

BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA IN CHILDREN

Ovsyannikov D., Gitinov S., Belyashova M., Samsonovich M., Konstantinova A., Jakota D., Gorbunov A., Marcenkov Y., Turina I., Kustova O., Rogatkin P.R., Korsunski A.

Abstract

The article presents current information about bronchiolitis obliteransorganizing pneumonia in children, etiology, pathomorphology, clinical and image-diagnostics of this rare disease. Presents a series of four observations of children with bronchiolitis obliterans organizing pneumonia, confirmed at autopsy and in vivo using computed tomography of the thorax high resolution.
Vrach. 2015;26(9):2-6
pages 2-6 views

PRINCIPLESOF CHOICEH. PYLORIFIRST-LINE THERAPY: CURRENT STATE OF PROBLEM

Svistunov A., Osadchuk M., Osadchuk A.

Abstract

The purpose of the review. Presentat the present levelprinciples of choice offirst-line regimensfor eradication of Helicobacter pylori. Show ingepidemiological aspectsof H. pylori resistance to antibiotics, included in the first linecircuit. On the basis of evidence presented various schemes of eradication, taking in to account the nature of the antimicrobialresistant, and the degreeofefficiency of elimination H. pylori. High lightspromisingways of improvingantimicrobial therapy H. pylori-infection.
Vrach. 2015;26(9):7-11
pages 7-11 views

THE WORLD PRACTICE IN THE ASSESSMENT OF THE INTERCHANGEABILITY OF BIOENGINEERED DRUGS

Smirnov V., Krasnykh L., Merkulov V., Bunyatyan N., Ramenskaya G., Yeltsova E., Smolyarchuk E., Yegorenkov E., Bushmanova A.

Abstract

In this article, main terms and definitions related to biosimilars, generic and original drugs are given. Furthermore, history brief of biotechnical industry rise and development with drugs produced by bio objects is presented. Here, main differences between biosimilars and generic drugs are explained, as well as their difference from brand-name drug. Biotechnical process and main application area of biosimilars are reviewed. Rules and regulations in Russia and EU are analyzed.
Vrach. 2015;26(9):12-14
pages 12-14 views

MEDICATIONS TO TREAT MULTIPLE SCLEROSIS: THE PRESENT AND THE FUTURE

Volkov A., Krylova I.

Abstract

The paper considers basic medications to treat multiple sclerosis and their mechanisms of action.
Vrach. 2015;26(9):15-20
pages 15-20 views

ELTACIN® TREATMENT IN CHILDREN WITH AUTONOMIC DYSFUNCTION

Simakov A., Panina M., Chekuldaeva L., Obukhova S.

Abstract

He clinical efficacy of Eltacin was evaluated in children with autonomicстоверную динамику уже через 10-12 дней терапии Элтаци-ном, при этом в 87,0% случаев отмечен переход пациентов вdysfunction syndrome.
Vrach. 2015;26(9):21-24
pages 21-24 views

IMMUNOSTIMULATORY THERAPY FOR CHRONIC ADENOIDITIS FOR CHILDREN

Gizinger O., Korkmazov M., Shchetinin S.

Abstract

The results of the study of the efficacy of immunomodulator Ismigen® in children with recurrent chronicheskim adenoiditis.
Vrach. 2015;26(9):25-28
pages 25-28 views

ATTENTION DEFICIT/HYPERACTIVITY DISORDER: NOVELTY IN ITS INSTRUMENTAL DIAGNOSIS

Fesenko Y., Fesenko E., Fesenko E.

Abstract

The paper considers the capabilities of the instrumental diagnosis of attention deficit/hyperactivity disorder in children, which allows one to optimize diagnostic criteria for this disorder.
Vrach. 2015;26(9):29-31
pages 29-31 views

PREDICTION OF BRONCHOPULMONARY DYSPLASIA IN NEWBORN INFANTS WITH MULTIPLE ORGAN DYSFUNCTION

Serebryakova E., Volosnikov D.

Abstract

The incidence, probability and possibility of predicting bronchopulmonary dysplasia were studied in newborn infants with multiple organ dysfunction while determining the count of normoblasts in their peripheral blood.
Vrach. 2015;26(9):32-33
pages 32-33 views

CLINICAL AND LABORATORY DIAGNOSTICS OF STUNTING IN CHILDREN AND ADOLESCENTS

Atanesyan R., Klimov L., Uglova T., Kurianinova V., Stouan M., Dolbnya S., Abramskaya L., Andreeva E., Saneeva G.

Abstract

The article presents the differential clinical and laboratory and instrumental diagnostics 262 children and adolescents with various forms of dwarfism, in particular patients with idiopathic short stature, pituitary dwarfism and hereditary syndromes, accompanied by dwarfism. Conducted comprehensive analysisof patients with dwarfism various etiologies, demonstrates the dominance of patients with growth hormone deficiency in children with the most severe forms of stunting.
Vrach. 2015;26(9):34-36
pages 34-36 views

FALLOPIAN TUBE OBSTRUCTION: DIAGNOSIS VERIFICATION

Bugerenko К., Shcherbakova L., Bugerenko A., Panina O.

Abstract

A total of 285 laparoscopically operated patients with infertility of various origin were retrospectively studied. Substantial differences were found between the rate of presumptive and intraoperatively established diagnoses. Laparoscopy that is not only of high diagnostic value, but also a highly effective treatment for different types of female fertility should be performed without making a preliminary isolated examination of the patency of fallopian tubes.
Vrach. 2015;26(9):37-40
pages 37-40 views

IMMUNOMODULATORS IN THE COMBINATION THERAPY OF SKIN ULCER DEFECTS

Mildzikhova D., Sakania L., Denisova E., Korsunskaya I.

Abstract

Combination therapy encompassing vascular, antioxidant, and immunomodulatory agents, added by topical treatment in terms of the phase of a wound process, makes it possible to rapidly cleanse and heal ulcer defects and to reduce both the length of hospital stay and the number of complicated and recurrent forms of the disease.
Vrach. 2015;26(9):41-43
pages 41-43 views

INTERGENIC INTERACTIONS IN THE DEVELOPMENT OF SILENT MYOCARDIAL ISCHEMIA

Khabibulina М.

Abstract

A study of a differently marked genetic component of the above-mentioned disease is a promising method in identifying a risk for cardiovascular diseases and in predicting their outcomes.
Vrach. 2015;26(9):44-46
pages 44-46 views

CHOICE OF A PROBIOTIC FOR INFECTIOUS DIARRHEA IN CHILDREN: IS THERE A PROBLEM?

Bekhtereva M., Komarova A., Ivanova V.

Abstract

Adequate and timely rehydration, diet therapy, and enterosorption using synbiotics with proven efficacy and convenient dosing are the mainstay of therapy for any type of diarrhea (including infectious one).
Vrach. 2015;26(9):47-51
pages 47-51 views

MEDICATION AS POSSIBILITY OF FUNCTIONAL REHABILITATION’S IMPROVEMENT IN STROKE PATIENTS

Kovalchuck V., Tokareva E.

Abstract

An influence of Dusopharm on functional rehabilitation in stroke patients has been studied. We’ve analysed the results of treatment of 650 ischemic stroke patients. The functional rehabilitation was followed up using Barthel, Lindmark, Scandinavian and Merton and Sutton scales, psychoemotional condition - Beck Depression Questionnaire and Wakefield Depression Scale, quality of life - Sickness Impact Profile. The results of the study revealed that the use of Dusopharm was well founded in the treatment of stroke patients for increase a functional rehabilitation and improvement of psychoemotional condition and the quality of life.
Vrach. 2015;26(9):52-54
pages 52-54 views

THE COURSE OF PREGNANCY IN WOMEN WITH HEART MULTIVALVE PROSTHESES

Adilova L., Adamyan L., Lyashko Е., Shifman E., Tyulkina Е., Konysheva O., Lukina N., Lapochkina О.

Abstract

The paper describes 3 clinical cases demonstrating the complicated course of pregnancy and labor in women with heart multivalve prostheses.
Vrach. 2015;26(9):55-58
pages 55-58 views

CLINICAL AND MORPHOLOGICAL CHARACTERISTICS OF MEDIASTINAL GRAY ZONE LYMPHOMA

Artemyeva A., Motalkina M., Zvyagintseva D., Semiglazov T., Frank G.

Abstract

Mediastinal gray zone lymphoma is a rare intermediate variant between classical Hodgkin lymphoma and primary mediastinal large B-cell lymphoma. When adiscrepancy is found between their morphological pattern and immunophenotype, the risk of mediastinal gray zone lymphoma should be thought.
Vrach. 2015;26(9):59-62
pages 59-62 views

HUMAN PAPILLOMAVIRUS TYPES 52, 58, 59 AND CERVICAL INTRAEPITHELIAL NEOPLASIA

Klinyshkova T., Buyan M., Samosudova I.

Abstract

The paper gives the results of examining patients with cervical papillomavirus infection associated with human papillomavirus (HPV) types 52, 58, and 59. The specific features of the pattern of the infection, viral load in cervical intraepithelial neoplasia versus other forms of cervical HPV infection are established.
Vrach. 2015;26(9):63-66
pages 63-66 views

THERAPEUTIC POTENTIAL OF THIOCETAM

Ivashev M., Gorbunov V.

Abstract

Data on application of a complex preparation are presented to tiotsetam in article at disorders of the blood circulatory system in a cardiac muscle and tissue of a brain
Vrach. 2015;26(9):67-68
pages 67-68 views

IMPACT OF THE LEVEL OF GENERAL PRACTITIONERS’ KNOWLEDGE ON THE QUALITY OF DIAGNOSIS OF UNCONTROLLED ASTHMA IN A POLYCLINIC

Pozdnyakova O., Baida A.

Abstract

General practitioners’ knowledge of current guidelines for the diagnosis and treatment of uncontrolled asthma in a polyclinic was studied. Their knowledge level was detected to be low. A clear correlation was found between physicians’ knowledge and the quality of early diagnosis and treatment of uncontrolled asthma.
Vrach. 2015;26(9):69-70
pages 69-70 views

OUTCOMES OF YERSINIA INFECTION IN CHILDREN

Bekhtereva M., Purin V., Panova T., Dutova Y., Ivanova V.

Abstract

Yersiniosis is an infectious disease that requires a diagnostic search from respiratory and enteric infections to systemic diseases. The paper describes cases of a fatal outcome of yersiniosis and those of hemophagocytic syndrome in the outcome of the diseases.
Vrach. 2015;26(9):71-73
pages 71-73 views

A NOVEL COMBINED TOPICAL AGENT FOR THE TREATMENT OF CHRONIC VULVOVAGINITIS

Sarvilina I., Kuzmina N.

Abstract

The efficiency and safety of treatment for chronic vulvovaginal infection with a novel topical agent containing metronidazole and miconazole (Metromicon-Neo® vaginal suppositories, Aveksima, Russia) were evaluated by analyzing different clinical and laboratory parameters and susceptibility to antimicrobial drugs and by assessing quality of life in patients through with the SF-26 questionnaire.
Vrach. 2015;26(9):74-80
pages 74-80 views

FUNCTIONAL IMMUNOMORPHOLOGY OF THE SPLEEN DURING ANTIPSYCHOTIC THERAPY

Volkov V.

Abstract

There are signs of suppressed splenic immune function in response to the side effects of neuroleptics during their treatment for as long as 6 months. Thereafter, the above function stabilizes. The intake of antipsychotic medications over 5 years is accompanied by a progressive reduction in the body’s adaptation potential.
Vrach. 2015;26(9):81-83
pages 81-83 views

EATING DISORDERS IN CLINICAL PRACTICE: TWO SIDES OF ONE PROBLEM

Vasilkova T., Mataev S., Rybina U.

Abstract

The paper considers the problem of eating disorders in the clinical practice of a physician and discusses the problems of healthy eating.
Vrach. 2015;26(9):84-88
pages 84-88 views

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