USE OF L-CARNITINE IN GENERAL MEDICAL PRACTICE
- 作者: Sizova Z.1, Shikh E.1, Makhova A.1
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隶属关系:
- I.M. Sechenov First Moscow State Medical University (Sechenov University)
- 期: 卷 30, 编号 4 (2019)
- 页面: 20-27
- 栏目: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/113029
- ID: 113029
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详细
The paper presents the results of a number of experimental and clinical studies proving the prospects for using L-carnitine in the clinic of internal diseases. Due to its antioxidant and antihypoxant properties, L-carnitine used in addition to the main etiopathogenetic therapy is prescribed by cardiologists, nephrologists, neurologists, and gerontologists. The experimental studies previously conducted by the authors showed no effect of L-carnitine on cytochrome P450 3A4 activity, which lowers the risk of P450 (CYP) 3A4 metabolic drug interactions. When used as part of comprehensive pharmacotherapy, L-carnitine has an increased safety profile in comorbid patients taking the drug.
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作者简介
Zh. Sizova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: sizova-klinfarma@mail.ru
Professor, MD
E. Shikh
I.M. Sechenov First Moscow State Medical University (Sechenov University)Professor, MD
A. Makhova
I.M. Sechenov First Moscow State Medical University (Sechenov University)Candidate of Medical Sciences
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