Impact of bioregulation therapy on the course of retinitis pigmentosa in older people


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅或者付费存取

详细

The paper presents the results of 30-year clinical use of peptide retinoprotectors in the treatment of degenerative retinal diseases, retinitis pigmentosa in particular. The findings suggest that peptide retinoprotectors have a high clinical effect and that these peptide drugs are promising for use in older people.

全文:

受限制的访问

作者简介

S. Trofimova

Saint Petersburg Institute of Bioregulation and Gerontology

Email: dr.s.trofimova@gmail.com
Professor

Y. Datseris

OMMA Ophthalmology Hospital

MD; Professor thens, Greece

A. Trofimov

OOO «Tree of Life. Clinic»

MD Saint Petersburg

R. Diamanti

OMMA Ophthalmology Hospital

MD thens, Greece

参考

  1. Трофимова С.В., Нероева В.В. Влияние ретиналамина на течение пигментной дегенерации сетчатки у лиц пожилого и старческого возраста. Геронтология и гериатрия. 2004; 3: 188-91
  2. Трофимова С.В., Максимов И.Б., Нероев В.В. Регуляторное действие пептидов сетчатки. СПб: ИКФ «Фолиант», 2004; 160 с.
  3. Хавинсон В.Х., Линькова Н.С., Проняева В.Е. Методика создания монослоя клеток на базе органотипической культуры для тестирования физио логически активных веществ. Бюлл. экспер. биол. мед. 2012; 2: 759
  4. Хавинсон В.Х., Проняева В.Е., Линькова Н.С. и др. Пептидергическая регуляция дифференцировка эмбриональных клеток сетчатки. Клеточные технологии в биологии и медицине. 2013; 1: 57-60
  5. Anisimov V.N., Khavinson V.Kh. Peptide bioregulation of aging: results and prospects. Biogerontology. 2010; 11: 139. doi: 10.1007/s10522-009-9249-8
  6. Berson E.L., Rosner B., Sandberg M.A. Clinical trial of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatment. Arch. Ophthalmol. 2004; 122 (9): 1297-305. doi: 10.1001/archopht.122.9.1297
  7. Cremers F., Jose A. Molecular genetics of Leber congenital amaurosis. Hum. Molec. Genet. 2002; 11 (10): 1169-76. doi: 10.1093/hmg/11.10.1169
  8. Datseris Y., Diamanti R., Trofimova S. Results of many years of application of peptide bioregulators in patients with retinitis pigmentosa. In: Book of Abstracts. Proceedings of V European Congress of Preventive, Regenerative and Anti-Aging Medicine, St. Petersburg. September 8-10, 2016. SPb: FlyPrint, 2016; p. 31-2.
  9. Datseris Y., Diamanti R., Trofimova S. Retinoprotectiv effect of peptide bioregulators in treatment of retinitis pigmentosa. In: Book of Abstracts International symposium of experts «Effective current approaches in anti-aging medicine and gerontology», Sweden, 13-14 April, 2018; p. 30-3.
  10. Ferrari S., Iorio E., Barbaro V. et al. Retinitis pigmentosa: genes and disease mechanisms. Curr. Genomics. 2011; 1: 238-49. doi: 10.2174/138920211795860107
  11. Khavinson V. Peptides and Ageing. NeuroEndocrynol. Lett. 2002; 23 (Suppl. 3): 144.
  12. Khavinson V.Kh., Malinin V.V., Trofimova S.V. et al. Inductive activity of retinal peptides. Bull. Exp. Biol. Med. 2002 (А); 134 (5): 482.
  13. Khavinson V.Kh., Razumovsky M., Trofimova S. Pineal regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa. NeuroEndocrinol. Lett. 2002 (Б); 23 (4): 365.
  14. Khavinson V.Kh., Solov’ev A.Yu., Zhilinskii D.V. et al. Epigenetic aspects of peptide mediated regulation of aging. Advances in Gerontology. 2012; 2 (4): 277.
  15. Khavinson V.Kh., Zemchikhina V.N., Trofimova S.V. et al. Effect of peptides on proliferative activity of retinal and pigmented epithelial cells. Bull. Exp. Biol. Med. 2003; 135 (6): 597.
  16. Khavinson V.Kh., Malinin V.V. Gerontological Aspects of Genom Peptide Regulation. Basel (Switzerland): Karger AG, 2005; p. 104.
  17. Takano M. Brain derived neutrophic factor enhances neurite regeneration from retinal ganglion cells in aged human retina in vitro. Exp. Eye Res. 2002; 74 (2): 319-23. doi: 10.1006/exer.2001.1118
  18. Vanyushin B.F., Khavinson V.Kh. Short Biologically Active Peptides as Epigenetic Modulators of Gene Activity. W. Doerfler, P. Böhm (eds.). Epigenetics - A Different Way of Looking at Genetics. Springer International Publishing Switzerland, 2016; p. 69-90.

补充文件

附件文件
动作
1. JATS XML

版权所有 © Russkiy Vrach Publishing House, 2020