Endometrial pathology in postmenopausal women


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详细

Thickened endometrium and postmenopausal bleeding occurs in women with both benign endometrial lesions and uterine cancer. The purpose of the study was to assess endometrial pathology of postmenopausal women, in regards to clinical symptoms: thickened endometrium and abnormal uterine bleeding. Material and methods. A retrospective study involving case records of 622 postmenopausal women with a thickened endometrium >4 mm and/ or postmenopausal bleeding, who underwent hysteroscopy with subsequent sampling. Results. Of 474 patients with thickened uterine mucosa, 23,8% were found to have atrophic endometrium and 69,4% diagnosed with endometrial polyps. There were no any endometrial pathology among 27 women with postmenopausal bleeding and unthickened uterine mucosa. The remaining 121 patients had experienced thickened endometrium and postmenopausal bleeding and there were pathological findings including atrophic uterine mucosa (28,1%) and endometrial polyps (33,9%). However, benign endometrial lesions were associated with both symptoms in 18%, malignancies - 35%. Conclusion. The most common pattern observed in postmenopausal women with thickened uterine mucosa >4 mm was endometrial polyps and atrophy. Combination of thickened endometrium and postmenopausal bleeding usually indicate the presence of atypical hyperplasia and uterine cancer.

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作者简介

N. Ivanova

Medical Scientific Educational Center of Lomonosov Moscow State University

Candidate of Medical Sciences

M. Shamarakova

Center of planning family and reproduction Health Department of Moscow

Candidate of Medical Sciences

O. Panina

Lomonosov Moscow State University

Email: mshamarakova@yandex.ru
Professor, MD

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