STRESS-PROTECTIVE EFFICACY OF PERSEN ® FORTE


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详细

The paper presents the results ofa large-scale open-label trial to evaluate the efficacy and safety of Persen® forte in arresting the conditions associated with acute and chronic psychosocial stress in 50 650 health care facility outpatients followed-up by 6300 physicians (neurologists and therapists). After two-week Persen® forte therapy, a considerable improvement was reported by 87 and 63% ofpatients with symptoms ofchronic andacute stress, respectively. Persen® forte was excellently and well tolerated by 87 and 89% of male and female respondents, respectively.

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作者简介

O. Vorobyeva

I.M. Sechenov First Moscow State Medical University

Email: ovvorobeva@mail.ru

参考

  1. Воробьева O. В., Рябоконь И. В. Открытое наблюдательное исследование стрессопротективной эффективности препарата Персен // РМЖ., - 2011; 19 (15): 979-984.
  2. Donath F., Quispe S., Diefenbach K. et al. Critical evaluation of the effect of valerian extract on sleep structure and sleep quality // Pharmacopsychiatry. - 2000; 33: 47-53.
  3. Ortiz J., Nieves-Natal J., Chavez P. Effects of Valeriana officinalis extracts on [3H]flunitrazepam binding, synaptosomal [3H]GABA uptake, and hippocampal [3H]GABA release // Neurochem Res. - 1999; 24: 1373-1378.
  4. Santos M., Ferreira F., Cunha A. et al. Synaptosomal GABA release as influenced by valerian root extract- involvement of the GABA carrier // Arch. Int. Pharmacodyn. - 1994; 327: 220-231.
  5. Schulz H., Stolz C., Muller J. The effect of valerian extract on sleep polygraphy in poor sleepers: a pilot study // Pharmacopsychiatry. - 1994; 27: 147-151.
  6. Schumacher B., Scholle S., Holzl J. et al. Lignans isolated from valerian: identification and characterization of a new olivil derivative with partial agonistic activity at A1 adenosine receptors. // J. Nat. Prod. - 2002; 65: 1479-1485.

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