PROMISES OF THERAPY FOR AUTOIMMUNE HEPATITIS IN CHILDREN


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The proportion of autoimmune hepatitis (AIG) in the structure of liver diseases in children is 1.2-1.7%. AIG has no specific clinical picture in childhood, which makes its timely diagnosis and therapy difficult. The paper describes a diagnostic methodology and gives the results of a study of the efficiency of incorporation of the topical glucocorticoid budesonide into therapy for AIG. The expediency of inclusion into a treatment program for infants with AIG is scientifically justified.

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作者简介

A. Lavrova

Nizhni Novgorod Research Institute of Pediatric Gastroenterology, Ministry of Health and Social Development of Russia

Email: lavrova26@mail.ru
MD

L. Varnacheva

Nizhni Novgorod Research Institute of Pediatric Gastroenterology, Ministry of Health and Social Development of Russia

Candidate of Medical Sciences

S. Abramov

Nizhni Novgorod Research Institute of Pediatric Gastroenterology, Ministry of Health and Social Development of Russia

Candidate of Medical Sciences

参考

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  6. Dilger K., Alberer M., Busch A. et al. Pharmacokinetics and pharmacodynamics action of budesonide in children with Crohn’s disease // Aliment Pharmacol Ther. -2006; 23: 387-395.
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  8. Ferreire A., Roquete M., Toppa N. et al. Effect of treatment of hepatic histopathology in children and adolescents with autoimmune hepatitis // J. Pediatric Gastroenterology and Nutrition. - 2008; 46 (1): 65-70.

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