USE OF PANANGIN IN OUTPATIENTS WITH ARTERIAL HYPERTENSION DURING THE PERIOD OF SUMMER HEAT


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The effect of Panangin on electrolyte balance, a reaction of the cardiovascular system, psychological status, and quality of life (QL) was evaluated in patients with compensated arterial hypertension (AH) under hot summer conditions. The investigation enrolled 61 patients receiving therapy with antihypertensive drugs, including angiotensin-converting enzyme inhibitors (ACEI); Panangin (1 tablet thrice daily) was added to the basic therapy in 31 patients; other 30 patients formed a control group. During heat, all the patients in the Panangin group tended to diminish anxiety and to significantly improve QL, which were absent in the control group. The QL increment significantly correlated with the plasma concentrations of K+ and Mg++. The use of Panangin during the hot period, which gave rise to slightly raised systolic blood pressure and decreased heart rate, could promote better QL. According to the results of the investigation, Panangin may be used to improve QL in patients with compensated AH in the period of summer heat. The drug given in prophylactic doses is safe, including when it is used in combination with ACEI and in elderly patients.

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作者简介

F. Ageyev

A.L. Myasnikov Research Institute of Cardiology, Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development

Email: ageev@cardio.ru
Professor, MD; Research Dispensary Department

M. Smirnova

A.L. Myasnikov Research Institute of Cardiology, Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development

Candidate of Medical Sciences; Research Dispensary Department

P. Galaninsky

A.L. Myasnikov Research Institute of Cardiology, Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development

Research Dispensary Department

O. Svirida

A.L. Myasnikov Research Institute of Cardiology, Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development

Candidate of Medical Sciences; Research Dispensary Department

A. Kuzmina

A.L. Myasnikov Research Institute of Cardiology, Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development

Candidate of Medical Sciences; Research Dispensary Department

I. Patrusheva

A.L. Myasnikov Research Institute of Cardiology, Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development

Candidate of Medical Sciences; Research Dispensary Department

E. Nurallyev

A.L. Myasnikov Research Institute of Cardiology, Russian Cardiology Research-and-Production Complex, Ministry of Health and Social Development

Candidate of Medical Sciences; Research Dispensary Department

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