EFFECTS OF IVABRADINE AND ATENOLOL ON THE PARAMETERS OF CENTRAL AND PERIPHERAL PULSE WAVE CONTOURS IN PATIENTS WITH PRIOR MYOCARDIAL INFARCTION


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The trial including 40 patients (mean age 63 years) with angina on exertion and postinfarct cardiosclerosis compared the effects of ivabradine and atenolol on central blood pressure and the characteristics of a reflected wave. By comparatively reducing heart rate, atenolol and ivabradine were found to multidirectionally alter cardiac output duration and subendocardial viability ratio.

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