APOPTOSIS AND MALE FERTILITY
- 作者: Ploskonos M.1, Nikolaev A.1
-
隶属关系:
- Astrakhan State Medical Academy
- 期: 卷 25, 编号 3 (2014)
- 页面: 23-25
- 栏目: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/115887
- ID: 115887
如何引用文章
开放存取
##reader.subscriptionAccessGranted##
详细
The authors give the results of their and other authors’ investigations, which demonstrate the negative impact of apoptosis on sperm quality. In subfebrile males, the amount of ejaculated apoptotic spermatozoa correlates with their concentration, mobility, and morphological defects. The presently accumulated facts allow one to regard the laboratory signs of apoptosis (phosphatidylserine externalization, Fas expression on the cells, DNA fragmentation) as factors that decrease sperm fertility.
全文:
作者简介
M. Ploskonos
Astrakhan State Medical Academy
Email: ploskonoz@mail.ru
Candidate of Biological Sciences; Professor
A. Nikolaev
Astrakhan State Medical AcademyMD
参考
- Плосконос М.В. Методы определения апоптоза сперматозоидов (Обзор литературы) // Клин. лаб. диагн. - 2013; 4: 3-8.
- Benchaib M., Braun V., Lornage J. et al. Sperm DNA fragmentation decreases the pregnancy rate in an assisted reproductive technique // Hum. Reprod. - 2003; 18 (5): 1023-8.
- Buyalos R., Hubert G., Schiewe M. Poor fertility predictive value of the sperm chromatin structure assay (SCSA) is neutralized by sperm injection: case studies // Fertil. Steril. - 2004; 81 (3): 27-8.
- Gandini L., Lombardo F., Paoli D. et al. Study of apoptotic DNA fragmentation in human spermatozoa // Hum. Reprod. - 2000; 15: 830-9.
- Giwercman A., Richthoff J., Hjillund H. et al. Correlation between sperm motility and sperm chromatin structure assay parameters // Fertil. Steril. - 2003; 80 (6): 1404-12.
- Ji G., Gu A., Hu F. et al. Polymorphisms in cell death pathway genes are associated with altered sperm apoptosis and poor semen quality // Hum. Reprod. -2009; 24 (10): 2439-46.
- Kierszenbaum A. Apoptosis during spermatogenesis: the thrill of being alive // Mol. Reprod. Dev. - 2001; 58: 1-3.
- Kruger T., Menkveld R., Stander F. et al. Sperm morphologic features as a prognostic factor in in vitro fertilization // Fertil. Steril. - 1986; 46: 1118-23.
- Lin W., Lamb D., Wheeler T. et. al. In situ end-labeling of human testicular tissue demonstrates increased apoptosis in conditions of abnormal spermatogenesis // Fertil. Steril. - 1997; 68: 1065-9.
- Muratori M., Marchiani S., Tamburrino L. et al. Nuclear staining identifies two populations of human sperm with different DNA fragmentation extent and relationship with semen parameters // Hum. Reprod. - 2008; 23 (5): 1035-43.
- Oosterhuis G., Mulder A., Kalsbeek-Batenburg E. et al. Measuring apoptosis in human spermatozoa: a biological assay for semen quality? // Fertil Steril. - 2000; 74: 245-50.
- Ramos L., Wetzels A. Low rates of DNA fragmentation in selected motile human spermatozoa assessed dy the TUNEL assay // Hum. Reprod. - 2001; 16 (8): 1703-7.
- Ricci G., Perticarari S., Fragonas E. et al. Apoptosis in human sperm: its correlation with semen quality and the presence of leukocytes // Hum. Reprod. -2002; 17: 2665-72.
- Sakkas D., Mariethoz E., St. John J. Abnormal sperm parameters in Humans are indicative of an abortive apoptotic mechanism linked to the Fasmediated pathway // Exp. Cell Res. - 1999; 251: 350-5.
- Shen H.-M., Dai J., Chia S.-E. et al. Detection of apoptotic alterations in sperm in subfertile patients and their correlations with sperm quality // Hum. Reprod. - 2002; 17: 1266-73.
补充文件
