APOPTOSIS AND MALE FERTILITY


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Abstract

The authors give the results of their and other authors’ investigations, which demonstrate the negative impact of apoptosis on sperm quality. In subfebrile males, the amount of ejaculated apoptotic spermatozoa correlates with their concentration, mobility, and morphological defects. The presently accumulated facts allow one to regard the laboratory signs of apoptosis (phosphatidylserine externalization, Fas expression on the cells, DNA fragmentation) as factors that decrease sperm fertility.

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About the authors

M. Ploskonos

Astrakhan State Medical Academy

Email: ploskonoz@mail.ru
Candidate of Biological Sciences; Professor

A. Nikolaev

Astrakhan State Medical Academy

MD

References

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