Features of mild duration asthma diagnostics in childbearing aged females

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详细

Asthma diagnostics especially of it’s mild forms, is considered to be a serious problem within primary health care unit due to the absence of exact evaluation algorithm of subjective, clinical and functional manifestations.

Objective. The goal of our study was to create recommendation on early asthma diagnostics in childbearing aged females, based on particular analysis of complaints, clinical and functional test results and to make them available to all primary medical care units.

Materials and methods. 2460 females of childbearing age with various severity of asthma duration were studied with complex of clinic and functional methods.

Results. Patients with various grades of asthma severity could be compliant free, same time the can appear signs of bronchial obstruction during auscultation. The marked discordance leads to mismatch in therapy administration. PEF50 decrease while initial spirometry and its’ increase after probe with bronchodilator is considered to be the earliest sign of bronchial obstruction. Asthma diagnostics at prehospital stage is to based upon complete chart collection, complaints analysis, auscultation signs while forced expiration as well as on spirography data on volume and forced expiration dynamics and PEF50.

Conclusion. Results of large population study on clinical feature of asthma duration and functional diagnostics of mild asthma duration could be recommended for primary health care physicians as method of early asthma diagnostics and therapy administration.

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作者简介

O. Lavrova

I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Heath of Russia

Email: loverova@bk.ru

MD, PhD

俄罗斯联邦, Saint Petersburg

M. Petrova

I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Heath of Russia

编辑信件的主要联系方式.
Email: loverova@bk.ru

Professor, MD, PhD

俄罗斯联邦, Saint Petersburg

M. Lukyanova

I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Heath of Russia

Email: loverova@bk.ru
俄罗斯联邦, Saint Petersburg

参考

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补充文件

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1. JATS XML
2. Fig. 1. Symptoms and auscultatory features of bronchial obstruction

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3. Fig. 2. Prevalence of patients with varying degrees of asthma severity with normal vital capacity, forced expiratory volume in the first second (FEV1), peak expiratory flow rate 50% (PEF50), FEV1/forced vital capacity of lungs

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4. Fig. 3. Frequency of occurrence of changes in external respiratory function indices at normal values of FEV1

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5. Fig. 4. Changes in airway resistance and specific airway conductance indices in patients without abnormalities according to spirography data

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