Optimization of diagnostics of urogenital tract infections caused by obligate pathogens in women

E. V. Lipova; Липова Е. В.; Yu. G. Vitvitskaya; Витвицкая Ю. Г.; I. I. Glazko; Глазко И. И.; E. A. Karasev; Карасев Е. А.; V. N. Volgin; Волгин В. Н.

doi:10.29296/25877305-2025-01-05

Optimization of diagnostics of urogenital tract infections caused by obligate pathogens in women

作者: Lipova E.V.¹, Vitvitskaya Y.G.¹, Glazko I.I.¹, Karasev E.A.¹, Volgin V.N.¹
隶属关系:
1. State Research Center – A.I. Burnazyan Federal Medical Biophysical Center of the Federal Medical and Biological Agency of Russia
期: 卷 36, 编号 1 (2025)
页面: 25-29
栏目: For Diagnosis
URL: https://journals.eco-vector.com/0236-3054/article/view/676820
DOI: https://doi.org/10.29296/25877305-2025-01-05
ID: 676820

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详细

Sexually transmitted infections remain an important medical and social problem. Untimely detection and, accordingly, late initiation of treatment lead to chronicity of the infectious-inflammatory process and the development of complications such as infertility.

Purpose. Assess the validity of diagnosing an infectious-inflammatory process based on the results of a microscopic examination - leukocyte reaction.

Material and methods. A retrospective analysis of medical records of 102 women was carried out, the results of microscopic examination, polymerase chain reaction (PCR), and real-time PCR were analyzed.

Results. The clinical picture in patients with obligate pathogens and patients with an inflammatory process caused by opportunistic microorganisms did not differ significantly: slightly and moderately severe clinical symptoms predominated. The infectious-inflammatory process caused by obligate pathogens was accompanied by an increase in the number of polymorphonuclear leukocytes only in 22.73% of cases; in other cases, the pathological process proceeded without a leukocyte reaction.

Conclusion. When diagnosing an infectious-inflammatory process, it is necessary to use not only routine methods, but also screening studies aimed at excluding obligate pathogens.

关键词

infectious diseases, obligate pathogens, polymerase chain reaction, opportunistic microorganisms, leukocyte reaction

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参考

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