Optimization of diagnostics of urogenital tract infections caused by obligate pathogens in women
- Authors: Lipova E.V.1, Vitvitskaya Y.G.1, Glazko I.I.1, Karasev E.A.1, Volgin V.N.1
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Affiliations:
- State Research Center – A.I. Burnazyan Federal Medical Biophysical Center of the Federal Medical and Biological Agency of Russia
- Issue: Vol 36, No 1 (2025)
- Pages: 25-29
- Section: For Diagnosis
- URL: https://journals.eco-vector.com/0236-3054/article/view/676820
- DOI: https://doi.org/10.29296/25877305-2025-01-05
- ID: 676820
Cite item
Abstract
Sexually transmitted infections remain an important medical and social problem. Untimely detection and, accordingly, late initiation of treatment lead to chronicity of the infectious-inflammatory process and the development of complications such as infertility.
Purpose. Assess the validity of diagnosing an infectious-inflammatory process based on the results of a microscopic examination - leukocyte reaction.
Material and methods. A retrospective analysis of medical records of 102 women was carried out, the results of microscopic examination, polymerase chain reaction (PCR), and real-time PCR were analyzed.
Results. The clinical picture in patients with obligate pathogens and patients with an inflammatory process caused by opportunistic microorganisms did not differ significantly: slightly and moderately severe clinical symptoms predominated. The infectious-inflammatory process caused by obligate pathogens was accompanied by an increase in the number of polymorphonuclear leukocytes only in 22.73% of cases; in other cases, the pathological process proceeded without a leukocyte reaction.
Conclusion. When diagnosing an infectious-inflammatory process, it is necessary to use not only routine methods, but also screening studies aimed at excluding obligate pathogens.
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About the authors
E. V. Lipova
State Research Center – A.I. Burnazyan Federal Medical Biophysical Center of the Federal Medical and Biological Agency of Russia
Author for correspondence.
Email: kursld@mail.ru
Professor, MD
Russian Federation, MoscowYu. G. Vitvitskaya
State Research Center – A.I. Burnazyan Federal Medical Biophysical Center of the Federal Medical and Biological Agency of Russia
Email: kursld@mail.ru
Candidate of Medical Sciences
Russian Federation, MoscowI. I. Glazko
State Research Center – A.I. Burnazyan Federal Medical Biophysical Center of the Federal Medical and Biological Agency of Russia
Email: kursld@mail.ru
Candidate of Medical Sciences; Associate Professor
Russian Federation, MoscowE. A. Karasev
State Research Center – A.I. Burnazyan Federal Medical Biophysical Center of the Federal Medical and Biological Agency of Russia
Email: kursld@mail.ru
Candidate of Medical Sciences
Russian Federation, MoscowV. N. Volgin
State Research Center – A.I. Burnazyan Federal Medical Biophysical Center of the Federal Medical and Biological Agency of Russia
Email: kursld@mail.ru
MD
Russian Federation, MoscowReferences
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