Malnutrition is an important factor in the development of protein-energy malnutrition in patients on program hemodialysis: yes or no?

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The development of protein-energy malnutrition (PEM) in patients on program hemodialysis is one of the pressing health problems. However, today there is no single point of view on the mechanisms of development of PEM in this cohort of patients.

Purpose. To evaluate the impact of malnutrition in the pathogenesis of PEM in patients receiving treatment with program hemodialysis.

Material and methods. The study involved 645 patients receiving treatment with program hemodialysis (300 men and 345 women).

Results. Signs of malnutrition were observed in 61 (9.5%) patients, including inadequate protein intake in 27 (4.19%), inadequate energy intake in the diet in 21 (3.26%), inadequate protein intake and inadequate energy intake in the diet – in 13 (2.02%). In patients with inadequate protein intake and inadequate energy supply in the diet, according to the food diary, statistically significantly lower values of the main indicators of nutritional status were revealed compared to the group of patients with adequate protein intake and energy supply in the diet.

Conclusion. Malnutrition remains one of the significant factors in the development of PEM in patients on hemodialysis.

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作者简介

A. Yakovenko

I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia (Pavlov University)

编辑信件的主要联系方式.
Email: leptin-rulit@mail.ru
ORCID iD: 0000-0003-1045-9336

Candidate of Medical Sciences

俄罗斯联邦

Yu. Lavrishcheva

V.A. Almazov National Medical Research Centre, Ministry of Health of Russia, Ministry of Health of Russia

Email: leptin-rulit@mail.ru
ORCID iD: 0000-0002-3073-2785

Candidate of Medical Sciences

俄罗斯联邦, Saint Petersburg

N. Ivanova

Next Level Events LLC

Email: leptin-rulit@mail.ru
阿拉伯联合酋长国, Dubai

A. Belskikh

S.M. Kirov Military Medical Academy

Email: leptin-rulit@mail.ru
ORCID iD: 0000-0002-0421-3797

Professor, Corresponding Member of the Russian Academy of Sciences, MD

俄罗斯联邦, Saint Petersburg

参考

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  2. Kang S.S., Chang J.W., Park Y. Nutritional Status Predicts 10-Year Mortality in Patients with End-Stage Renal Disease on Hemodialysis. Nutrients. 2017; 9 (4): pii:E399. doi: 10.3390/nu9040399
  3. Fouque D., Kalantar-Zadeh K., Kopple J. et al. A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease. Kidney Int. 2008; 73 (4): 391–8. doi: 10.1038/sj.ki.5002585
  4. Perez Vogt B., Costa Teixeira Caramori J. Are Nutritional Composed Scoring Systems and Protein-Energy Wasting Score Associated With Mortality in Maintenance Hemodialysis Patients? J Ren Nutr. 2016; 26 (3): 183–9. doi: 10.1053/j.jrn.2015.11.003
  5. Obi Y., Qader H., Kovesdy C.P. et al. Latest consensus and update on protein-energy wasting in chronic kidney disease. Curr Opin Clin Nutr Metab Care. 2015; 18 (3): 254–62. doi: 10.1097/MCO.0000000000000171
  6. Wang X.H., Mitch W.E. Mechanisms of muscle wasting in chronic kidney disease. Nat Rev Nephrol. 2014; 10 (9): 504–16. doi: 10.1038/nrneph.2014.112
  7. Ikizler T.A., Burrowes J.D., Byham-Gray L.D. et al; KDOQI Nutrition in CKD Guideline Work Group. KDOQI clinical practice guideline for nutrition in CKD: 2020 update. Am J Kidney Dis. 2020; 76 (3suppl1): S1-S107. doi: 10.1053/j.ajkd.2020.05.006

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