Prognostic criteria for the proliferative potential of the endometrium in the perimenopausal period
- Authors: Grishchenko VI1, Kachailo IA1, Muryzina IY.1
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Affiliations:
- Kharkov National Medical University, Ukraine
- Issue: No 6 (2009)
- Pages: 33-38
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/246266
- ID: 246266
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Abstract
An association of metabolic disturbances with the imbalance of endometrial proliferation and apoptosis and a possibility of using sFas as a diagnostic criterion for the proliferative potential of endometrial glandular epitheliocytes were studied in perimenopausal women with different forms of hyperplasia of the mucous membrane of the corpus uteri in the presence of the metabolic syndrome. The authors show it expedient to single out a group at risk for malignancy of the hyperplastic endometrium. In endometrial hyperplasia, the determination of sFas may serve as a prognostic criterion for a risk of atypical transformation.
About the authors
V I Grishchenko
Kharkov National Medical University, Ukraine
Email: meduniver@khnmu.bestnet.ua
Kharkov National Medical University, Ukraine
I A Kachailo
Kharkov National Medical University, Ukraine
Email: meduniver@khnmu.bestnet.ua
Kharkov National Medical University, Ukraine
I Yu Muryzina
Kharkov National Medical University, Ukraine
Email: meduniver@khnmu.bestnet.ua
Kharkov National Medical University, Ukraine
References
- Глоба Э. В. // Ендокрiнологiя. - 2004. - Т. 9, № 1. - С. 78-88.
- Коломиец Л. А., Чернышева А. Л., Крицкая Н. Г., Бочкарева Н. В. Клинико-морфобиохимические аспекты гиперпластических аспектов и рака эндометрия. - Томск, 2003.
- Кулаков В. И., Сухих Г. Т., Гатаулина Р. Г. // Пробл. репрод. - 1999. - № 2. - С. 15-26.
- Медицина климактерия / Под ред. В. П. Сметник. - М., 2006.
- Подзолкова И. М., Подзолков В. И., Глазкова О. Л., Топольская И. В. // Акуш. и гин. - 2003. - № 6. - С. 28-33.
- Резников А. Г. // Журн. АМНУ. - 2003. - № 3. - С. 423-437.
- Федосов А. В., Семейкин А. В. // Вопр. онкол. - 2003. - Т. 49, № 1. - С. 9-18.
- Хорошева Г., Беркетова Т. // Врач. - 2003. - № 3. С. 6-7.
- Carranza L. S., Murillo U., Martinez T., Santos G. J. // Int. J. Fertil. - 1998. - Vol. 43. - P. 306-311.
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