HOMOCYSTEINE, MTHFR GENE POLYMORPHISMS, AND PREGNANCY COMPLICATIONS


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Abstract

The review discusses the current views on the role of polymorphic variants of the MTHFR gene in the development of obstetric diseases in the light of the contradictory results of studies revealing the associations of markers of this locus with complicated pregnancy.

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About the authors

E. A TRIFONOVA

Research Institute of Medical Genetics, Siberian Branch, Russian Academy of Medical Sciences

Email: ekaterina.trifonova@medgenetics.ru

T. V GABIDULINA

Siberian State Medical University, Russian Agency for Health Care

T. A AGARKOVA

Research Institute of Obstetrics, Gynecology, and Perinatology, Siberian Branch, Russian Academy of Medical Sciences, Tomsk

N. A GABITOVA

Research Institute of Obstetrics, Gynecology, and Perinatology, Siberian Branch, Russian Academy of Medical Sciences, Tomsk

V. A STEPANOV

Research Institute of Medical Genetics, Siberian Branch, Russian Academy of Medical Sciences

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