PATHOPHYSIOLOGICAL MECHANISMS OF DEVELOPMENT OF NEUROLOGICAL COMPLICATIONS OF ECLAMPSIA: SYSTEMS REVIEW


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Abstract

This study attempted to systematize and summarize the hypotheses concerning the pathophysiological mechanisms of development of neurological complications due to eclampsia, which had been advanced in the considered studies and clinical trials, on the basis of the data obtained during their performance. The recommendations proposed in these studies for the treatment and prevention of neurological complications of eclampsia were also collected and systematized. The material collected was analytically reviewed to reveal major problems to be further investigated and to raise the questions to which there were so far no clear answers objectively confirmed by clinical trials.

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About the authors

E. M SHIFMAN

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Email: e_shifman@oparina4.ru

S. E FLOKA

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

G. P TIKHOVA

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

N. V KHRAMCHENKO

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

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