ANALYSIS OF THE ASSOCIATIONS OF GENE POLYMORPHISMS WITH POLYCYSTIC OVARY SYNDROME AND ENDOCRINE AND METABOLIC DISTURBANCES
- Authors: SUKHIKH G.T1, BIRYUKOVA A.M1, NAZARENKO T.A1, ZAKHARZHEVSKAYA N.B2, DURINYAN E.R2, GENEROZOV E.V2, GOVORUN V.M2
-
Affiliations:
- Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
- Research Institute of Physicochemical Medicine, Federal Biomedical Agency
- Issue: No 5 (2011)
- Pages: 49-53
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/246525
- ID: 246525
Cite item
Abstract
Full Text
About the authors
G. T SUKHIKH
Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
Email: g_sukhikh@oparina.ru
A. M BIRYUKOVA
Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
T. A NAZARENKO
Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
N. B ZAKHARZHEVSKAYA
Research Institute of Physicochemical Medicine, Federal Biomedical Agency
E. R DURINYAN
Research Institute of Physicochemical Medicine, Federal Biomedical Agency
E. V GENEROZOV
Research Institute of Physicochemical Medicine, Federal Biomedical Agency
V. M GOVORUN
Research Institute of Physicochemical Medicine, Federal Biomedical Agency
References
- Андреева Е.Н., Семичева Т.В., Веснина А.Ф. и др. Молекулярно-генетические аспекты патогенеза СПКЯ // Пробл. репрод. - 2007. — Т. 13, № 6. — С. 29—35.
- Андреева Е.Н., Веснина А.Ф., Семичева Т.В. и др. Особенности клинических проявлений СПКЯ у больных с полиморфизмом в гене инсулина INS V NTP // Пробл. репрод. — 2008. — № 1. — С.
- Веснина А.Ф., Андреева Е.Н., Семичева Т.В. Особенности углеводного обмена и чувствительности к инсулину у больных при генотипических отличиях по полиморфизму// Репродуктивное здоровье семьи: Материалы 2-го Международного конгресса по репродуктивной медицине. — М., 2008.
- Дедов И.И., Мельниченко Г.А. Синдром поликистозных яичников: Руководство для врачей— М.: МИА, 2007.
- Сухих Г.Т., Бирюкова А.М., Назаренко Т.А., Дуринян Э.Р. Эндокринно-метаболические особенности у пациенток с синдромом поликистозных яичников// Акуш. и гин. — 2011. — № 4 — С. 45—49.
- Amato P., Simpson J.L. The genetics of polycystic ovary syndrome // Best. Pract. Res. Clin. Obstet. Gynaecol. -2005. - Vol. 18. - Р. 707-718.
- Diamanti-Kandarakis E., Piperi C. Genetics of polycystic ovary syndrome: searching for the way out of the labyrinth // Hum. Reprod. Update. — 2005. — Vol. 11. — Р. 631-643.
- Ehrmann D.A. Polycystic ovary syndrome// N. Engl. J. Med. — 2005. — Vol. 352. — Р.1223-1236.
- Ehrmann D.A., Tang X., Yoshiuchi I. et al. Relationship of insulin receptor substrate-1 and 2 genotypes to phenotypic features of polycystic ovary syndrome.// J. Clin. Endocrinol. Metab. - 2002. - Vol. 87. - Р. 4297- 4300.
- El Mkadem S.A., Lautier C., Macari F. et al. Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to severe insulin resistance of women with polycystic ovary syndrome // Diabetes. - 2001. - Vol. 50. -Р. 2164-2168.
- Jahanfar S., Eden J.A. Genetic and non-genetic theories on the etiology of polycystic ovary syndrome // Gynecol. Endocrinol. - 1996. - Vol. 10. - Р. 357-364.
- Nobels F., Dewailly D. Puberty and polycystic ovarian syndrome: the insulin/insulin-like growth factor I hypothesis // Fertility and Sterility. - 1992. — Vol. 58, № 4. — Р. 655—666.
- Qin K., Ehrmann D.A., Cox N. et al. Identification of functional polymorphism of the human type 5 17beta-hydroxysteroid dehydrogenase gene associated with polycystic ovary syndrome // J. Clin. Endocrinol. Metab. — 2006. - Vol. 91, № 1. - Р. 270—276.
- Roeder K., Bacanu S.A., Wasserman L., Devlin B. Using linkage genome scans to improve power of association in genome scans // Am. J. Hum. Genet. — 2006. — Vol. 78. — Р. 243-252.
- Sir-Petermann T., Perez-Bravo F., Angel B. et al. G972R polymorphism of IRS-1 in women with polycystic ovary syndrome // Diabetologia. - 2001. -Vol. 44. - Р. 12001201.
- Villuendas G., Botella-Carretero J.I., Roldan B. et al. Polymorphisms in the insulin receptor substrate-1 (IRS-1) gene and the insulin receptor substrate-2 (IRS-2) gene influence glucose homeostasis and body mass index in women with polycystic ovary syndrome and non-hyperandrogenic controls// Hum. Reprod. - 2005. -Vol. 20. - Р. 3184-3191.
- Wu X.K., Zhou S.Y., Liu J.X. et al. Selective ovary resistance to insulin signaling in women with polycystic ovary syndrome// Fertil. and Steril. — 2003. — Vol. 80, № 4. — Р. 954-965.
- Zacur H.A. Polycystic ovary syndrome, hyperandrogenism, and insulin resistance// Obstet. Gynecol. Clin. — 2001. — Vol. 28, № 1. — Р. 21—33.