PREVENTION OF AFTERBIRTH AND EARLY POSTPARTUM HEMORRHAGE. WHAT DRUGS ARE TO BE USED?


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Abstract

This review examines the data currently available in the literature on the use of uterotonic drugs to prevent afterbirth and early postpartum hemorrhage. For this purpose, oxytocin, ergometrine preparations, and prostaglandin F2a and E1 analogues are used now. Different administration routes and doses of the drugs are considered; the frequency and severity of side effects are estimated. As of now, there is no convincing evidence for the predominant efficacy of any of the drugs. The WHO experts recommend oxytocin that has the lowest frequency of side effects as the drug of choice for the prevention of hemorrhage.

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About the authors

O. R BAYEV

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Email: o_baev@oparina4.ru

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