SYSTEMIC INFLAMMATORY RESPONSE SYNDROME AND PREGNANCY (A REVIEW OF LITERATURE)
- Authors: LOMOVA N.A1, ORDZHONIKIDZE N.V1, VANKO L.V1
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Affiliations:
- Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
- Issue: No 1 (2012)
- Pages: 23-27
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/246670
- ID: 246670
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Abstract
The paper sets forth current ideas on the mechanisms to develop a systemic inflammatory response during pregnancy. It considers different factors of innate immunity, which are involved in the development of complications, such as recurrent miscarriage, intrauterine growth retardation, preeclampsia, placental insufficiency syndrome, and intrauterine infection. The role of neutrophils and cytokines in the development of an inflammatory response is covered. Understanding of the pathophysiological mechanisms acting in the maternal-placental-fetal unit will make it possible to improve diagnostic methods and to perform pathogenetically sound therapy for obstetric complications.
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About the authors
N. A LOMOVA
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
Email: natasha-lomova@yandex.ru
N. V ORDZHONIKIDZE
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
L. V VANKO
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
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