THE OVARIAN RESERVE IN WOMEN WITH INFERTILITY AND AUTOIMMUNE THYROIDITIS


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Abstract

Objective. To assess ovarian reserve patterns in women with infertility and thyroid autoimmunity. Subjects and methods. Ovarian reserve parameters (FSH, AMH, ovarian volume, number of antral follicles) were assessed in 67 women with tubo-peritoneal infertility without operative interventions on the ovaries, aged from 29.3± 0.9 years including 31 women with thyroid autoimmunity (TAI) (main group) and 36 women without thyroid pathology (controls). Results. There is obvious evidence that women with AIT have a diminished ovarian reserve: higher FSH and lower AMH in young and middle-aged women, decreased ovarian volume, and a smaller number of antral follicles, which is likely to be associated with the autoimmune genesis of this pathology. Conclusion. Infertile women with TAI are a risk group for ovarian reserve decrease that demands highly efficient methods of restoration of reproductive function within minimum time limits

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About the authors

S. G PERMINOVA

Federal Research Center of Obstetrics, Gynecology, and Perinatology named after V.I. Kulakov Ministry of Health and Social Development of Russia

Email: S.perminova@oparina 4.ru

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