ROLE OF LACTULOSE IN THE COMBINATION TREATMENT OF INFLAMMATORY DISEASES OF THE URINARY TRACT IN PREGNANT WOMEN
- Authors: MOZGOVAYA E.E1, TALALEVA N.E1, DEDUL A.G2, OPARINA T.I1, PROKOPENKO V.M1
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Affiliations:
- D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch, Russian Academy of Medical Sciences
- Saint-Petersburg State University
- Issue: No 1 (2012)
- Pages: 108-112
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/246762
- ID: 246762
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Abstract
Objective. To optimize the results of treatment for urinary tract infections (UTI) in pregnant women, by using lactose (normaze) in their combination therapy. Subjects and methods. A study group consisted of 50 pregnant women with UTI who received normaze in addition to conventional therapy; a comparison group included 30 pregnant women with this condition who did not take normaze; a control group comprised 25 pregnant women without UTI. The magnitude of subjective questionnaire complaints was estimated; bacteriological study of the urogenital tract was conducted; ultrasonography of the pubic symphysis was performed in patients with symphysiopathy. The blood levels of magnesium and total and ionized calcium and the daily urinary excretion of magnesium and calcium were estimated. Results. There was a considerable improvement in stools, alleviated symptoms of mineral metabolic disturbances in pregnant women with UTI and a more significant correction of genital tract biocenosis in the patients receiving lactulose as part of combination treatment. Conclusion. Incorporation of normaze into the algorithm of treatment for pregnant women with UTI substantially affects the efficiency of the performed therapy due to its many-sided pathogenetic action on the symptom complex peculiar to patients with UTI during pregnancy.
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About the authors
E. E MOZGOVAYA
D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch, Russian Academy of Medical Sciences
Email: elmozg@mail.ru
N. E TALALEVA
D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch, Russian Academy of Medical Sciences
A. G DEDUL
Saint-Petersburg State UniversityDepartment of Obstetrics, Gynecology, and Reproductology, Faculty of Therapeutics
T. I OPARINA
D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch, Russian Academy of Medical Sciences
V. M PROKOPENKO
D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch, Russian Academy of Medical Sciences
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