THE ROLE OF PREIMPLANTATION GENETIC SCREENING FOR ENHANCEMENT OF INFERTILITY TREATMENT OUTCOMES IN PATIENTS WITH MULTIPLE FAILED IVF CYCLES


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Abstract

The current understanding about the comparative genomic hybridization — CGH is discussed in the review, which provides an alternative means of genome-wide screening for aneuploidy and microstructural chromosomal abnormalities at one time point for all chromosomes. Relative rate of aneuploidy in oocytes and blastocysts among patients with multiple failed IVF cycles by using CGH showed high frequency chromosomal abnormalities on meiotic and mitotic embryogenesis stages.

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About the authors

M. V SORVACHEVA

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian Federation

Email: Sorvacheva.86@mail.ru
Moscow, Russia

M. A VEYUKOVA

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian Federation

Email: veymary@gmail.com
Moscow, Russia

N. G MISHIEVA

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian Federation

Email: nondoc555@mail.ru
Moscow, Russia

A. N ABUBAKIROV

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian Federation

Email: nondoc555@yahoo.com
Moscow, Russia

L. V VINOGRADOVA

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian Federation

Email: Kalugina-LV@yandex.ru
Moscow, Russia

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