SPECIFICATION OF PERIOPERATIVE ANTIBIOTIC PROPHYLAXIS FOR LOWER INFECTIOUS RISK WOMEN UNDERGOING CESAERIAN SECTION


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Abstract

Objective. To compare outcomes (postpartum period rate and structure of complications) after caesarian sections in low risk for infection development women with normal vaginal flora Methods. Randomized control trial was conducted. Real time PCR was done to detect vaginal flora parameters. All women were randomized into 2 group for caesarian section perioperative antibiotic prophylaxis administration: group 1 (study) group — 75 women followed caesarian section without perioperative antibiotic prophylaxis; group 2 (compered) — 75 women with one time intravenous inhibitor-protected penicillin’s intraoperative antibiotic prophylaxis in standard dose. Results. 3 of all examined women (2%) followed by intraoperative antibiotic prophylaxis had complication in postpartum such as subinvolution of uterus (2/3) and subgaleal haematoma (1/3). Rest of them had no complication in postpartum period. Conclusion. 98% of women with or without antibiotic prophylaxis in the postpartum period had normal endometrial healing based on cytological screening of lochia, timely speed of uterus involution, may indicate opportunity of antibiotic administration abandonment during SC for this group of women.

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About the authors

A. A BALUSHKINA

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian Federation

Email: ann.balushkina@gmail.com
Moscow, Russia

N. E KAN

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian Federation

Email: kan-med@mail.ru
Moscow, Russia

V. L TYUTYUNNIK

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian Federation

Email: tioutiounnik@mail.ru
Moscow, Russia

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