CLINICAL AND ANAMNESTIC CHARACTERISTICS OF WOMEN WITH IDIOPATHIC PRETERM LABOR IN CASE OF A SLAVIC POPULATION


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Abstract

Objective. To study the role of clinical and anamnestic risk factors of preterm labor in a Slavic female population of Russia. Subject and methods. Three hundred and four women with idiopathic preterm labor (n = 92) and spontaneous term labor (n = 212) were examined. Their history data and overall clinical manifestations were examined in detail. The significance of the obtained results was calculated by statistical methods. Results. The women with preterm labor had significantly low educational level, frequently smoked more cigarettes during pregnancy, they were single or married twice or more. The family and their histories of preterm births were more common in women who had given birth to a premature baby. The women had often a history of infectious diseases, such as both sustained infections in childhood, frequent acute respiratory diseases in adulthood, and infectious and inflammatory diseases of reproductive organs. They had significantly more frequently an obstetric and gynecological history: abortions, spontaneous miscarriages, and infertility; preterm births proved to be the most important risk factor. Complicated pregnancy was also significantly more common in the preterm labor group. Conclusion. Identification of clinical and anamnestic risk factors makes it possible to predict the risk of preterm labor in a woman when planning and in the early stages of pregnancy and to more validly choose patient management tactics and preventive measures before the clinical signs of threatened preterm labor occur.

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About the authors

Zulfiya Sagdullaevna Khodzhaeva

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

M.D., Ph.D., Professor, Principal Investigator, Department of Maternal-Fetal Medicine 117997, Russia, Moscow, Oparina street, 4

Olga Igorevna Fedotovskaya

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: o_fedotovskaya@oparina4.ru
Postgraduate Student 117997, Russia, Moscow, Oparina street, 4

Andrey Evgen'evich Donnikov

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_donnikov@oparina4.ru
Ph.D. scientist of the laboratory of molecular genetics methods 117997, Russia, Moscow, Oparina street, 4

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