Impact of iodine prevention of autoimmune thyroiditis activity during pregnancy
- Authors: Sandakova E.A.1, Kapustina E.Y.1, Zalesnaya N.Y.2, Chudinov N.V.2
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Affiliations:
- Acad. E.A. Wagner Perm State Medical Academy, Ministry of Health of the Russian Federation
- OOO "Profimed Consulting Diagnostic Center
- Issue: No 1 (2014)
- Pages: 78-82
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/247177
- ID: 247177
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Abstract
Objective. To evaluate the thyroid status in relation to the duration of iodine intake in pregnant women with autoimmune thyroiditis living in iodine-deficient areas. Subject and methods. A group of 64 pregnant women with autoimmune thyroiditis was examined. The thyroid status (the levels of thyroid-stimulating hormone, free thyroxine, antithyroperoxidase and antithyroglobulin antibodies, thyroid ultrasound characteristics) was studied in patients after early and late iodine prevention. Results. The early and late iodine prevention groups showed no significant differences in the changes of the thyroid status in patients with autoimmune thyroiditis during pregnancy. The trend was toward a less need for L-thyroxine replacement therapy among the pregnant women who had early iodine prevention. Conclusion. Intake of physiological iodine doses during pregnancy not only fails to have a negative impact on the activity of an autoimmune process, but also contributes to more stable thyroid function in patients with autoimmune thyroiditis both during pregnancy and the postpartum period.
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About the authors
Elena Anatolyevna Sandakova
Acad. E.A. Wagner Perm State Medical Academy, Ministry of Health of the Russian Federation
Email: selenallperm@yandex.ru
professor, doctor of medicine, header of the department of obstetrics and gynaecology of advanced doctors' studies faculty
Ekaterina Yuryevna Kapustina
Acad. E.A. Wagner Perm State Medical Academy, Ministry of Health of the Russian Federation
Email: doc.kat@mail.ru
postgraduate of the department of obstetrics and gynaecology of advanced doctors' studies faculty
Natalya Yevgenyevna Zalesnaya
OOO "Profimed Consulting Diagnostic Center
Email: krasa-ru@yandex.ru
ultrasonographer Perm
Nikolay Valentinovich Chudinov
OOO "Profimed Consulting Diagnostic Center
Email: nchudinov.60@mail.ru
ultrasonographer Perm
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