Investigation of the myofibroblast layer separating the placenta from its bed
- Authors: Krasnyi A.M.1, Savilova A.M.1, Tetruashvili N.K1, Sukhikh G.T1
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Affiliations:
- Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
- Issue: No 12 (2014)
- Pages: 71-73
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/247306
- ID: 247306
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Abstract
Objective. To examine the maternal placental cytotrophoblast layer and to reveal the contractile capacities of its cells. Subjects and methods. Seven placentas from 25-30-year-old women with uncomplicated pregnancy and labor were examined. Fluorescent immunohistochemical staining of the maternal placenta was carried out. Anticytokeratin 7 and anti-alpha smooth muscle actin antibodies were used. Results. The apical surface of the placenta was shown to be covered with the myofibroblast network limiting the cytotrophoblast layer. Conclusion. The competence and activity of the myofibroblast network located in the apical portion of the cytotrophoblast layer can determine the normal separation of the placenta from the uterus during labor.
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About the authors
Aleksey M. Krasnyi
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: a_krasnyi@oparina4.ru
PhD Head. Laboratory of Cytology
Anastasia M. Savilova
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: a_savilova@oparina4.ru
PhD Head. Laboratory of Cell Technology
N. K Tetruashvili
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
G. T Sukhikh
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
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