ANALYSIS OF PERINATAL OUTCOMES OF VERY EARLY PREMATURE BIRTH


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Abstract

Background. There is an ambiguous approach to managing very early preterm deliveries and nursing extremely low birth weight infants. Objective. To estimate perinatal outcomes in relation to gestational age and delivery method at 22-27 weeks’ gestation. Subject and methods. All very early premature births occurring at the Moscow Regional Perinatal Center in 2010 to 2013 were analyzed compared with perinatal outcomes for extremely low birth weight neonatal infants in relation to gestational age and delivery method. Results. The babies born at 22-27 weeks’ gestation have intrauterine growth restriction in the majority of cases (43.5%); evaluation of the status of neonates born very preterm according to 1- and 5-minute Apgar scores suggests that the babies born at 22-24 weeks are very lowly viable. The increase in the rate of abdominal delivery in 2012-2013 compared to that in 2010-2011 (from 30 to 70%, respectively) resulted in a reduction in perinatal mortality as a whole (from 41,9 to 266.0%o, respectively). At 22-25 weeks’ gestation, the method of delivery does not affect survival rates in the children. Conclusion. Operative delivery is a significantly more sparing method for extremely low birth weight neonates at 26-27 weeks gestation.

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About the authors

Olga Fedorovna Serova

Moscow Regional Perinatal Center; A.I. Burnazyan Federal Medical Biophysical Center, Federal Biomedical Agency of Russia

Email: olga-serova@yandex.ru
head of department of obstetrics; postgraduate student of the Department of Obstetrics, Gynecology, and Perinatology Balashikha 143900, Shosse Enthusiastov 12, Moscow region, Russia; Moscow 123098, Marshala Novikova str. 23, Russia

Irina Vladimirovna Chernigova

Moscow Regional Perinatal Center; A.I. Burnazyan Federal Medical Biophysical Center, Federal Biomedical Agency of Russia

Email: mopc02@mail.ru
head of department of obstetrics; postgraduate student of the Department of Obstetrics, Gynecology, and Perinatology Balashikha 143900, Shosse Enthusiastov 12, Moscow region, Russia; Moscow 123098, Marshala Novikova str. 23, Russia

Ludmila Vladimirovna Sedaya

Moscow Regional Perinatal Center; A.I. Burnazyan Federal Medical Biophysical Center, Federal Biomedical Agency of Russia

Email: mopc02@mail.ru
PhD, deputy chief physician; head teacher of the Department of Obstetrics, Gynecology, and Perinatology Balashikha 143900, Shosse Enthusiastov 12, Moscow region, Russia; Moscow 123098, Marshala Novikova str. 23, Russia

Natalia Vyacheslavovna Shutikova

Moscow Regional Perinatal Center; A.I. Burnazyan Federal Medical Biophysical Center, Federal Biomedical Agency of Russia

Email: omo_2012@mail.ru
PhD, head of the organizational department; lecturer of the Department of Obstetrics, Gynecology, and Perinatology Balashikha 143900, Shosse Enthusiastov 12, Moscow region, Russia; Moscow 123098, Marshala Novikova str. 23, Russia

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