CURRENT TREATMENTS IN PATIENTS WITH CHRONIC ENDOMETRITIS


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Abstract

Objective. To study the efficiency of current treatments in patients with chronic endometritis (CE). Subject and methods. The currently available publications on current methods for the diagnosis and treatment of patients with CE were reviewed. Results. The opinion that it is expedient to perform two-stage combination therapy for CE has formed now. In the view of some specialists, the empirical use of antibacterial agents is justified; however, a number of authors believe that the species and quantitative composition of microorganisms detectable in the endometrial biopsy specimens should be kept in mind when prescribing the agents. Conclusion. Most modern-day investigations demonstrating different treatments for CE and analyzing the efficiency of its therapy are aimed at alleviating the clinical symptoms of the disease and at normalizing the endometrial ultrasound pattern. However, the latter should be examined pre- and postoperatively in order to adequately assess the therapy performed. The efficiency of etiotropic therapy for CE is largely determined by the accurate identification of its pathogen in the uterine mucosal biopsy specimens. Despite the great variety of proposed therapy options for CE, its treatment involves considerable methodic and practical problems. By taking into account the components of the pathogenesis of CE and new diagnostic possibilities, there must be a further search for innovative comprehensive approaches to treating CE.

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About the authors

Natalia A. Gombolevskaya

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: gombolevskaya@yandex.ru
a graduate student 117997, Russia, Moscow, Ac. Oparina str. 4

Larisa A. Marchenko

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: l.a.marchenko@yandex.ru
MD, professor, leading researcher of gynecological endocrinology department 117997, Russia, Moscow, Ac. Oparina str. 4

Vera V. Muraveva

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: v_muravieva@oparina4.ru
PhD, Senior Scientist of Microbiology Laboratory 117997, Russia, Moscow, Ac. Oparina str. 4

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