Comparison of the informative value of testing the biological material obtained from the cervical canal and vagina during examinations of non-pregnant patients for genital infections


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Objective. To estimate the informative value of testing the biological material from the cervical canal and vagina for the diagnosis of vulvovaginal and cervical infections in patients seeing a gynecologist. Subjects and methods. The investigation enrolled 206 non-pregnant patients. The biological material obtained from the cervical canal and vagina was tested by real-time polymerase chain reaction. Results. С. trachomatis and T. vaginalis were more frequently found in the vaginal samples. M. genitalium and N. gonorrhoreae were more common in the vaginal and cervical samples. Opportunistic genital mycoplasmas were also more frequently detected in the vaginal biomaterial; DNA concentrations in these microorganisms demonstrated a significant correlation in the vaginal and cervical samples. Conclusion. The informative value of testing the biological material obtained from the vagina is higher than that from the cervical canal during examinations of non-pregnant patents.

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作者简介

T. Rumyantseva

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare

Email: Ivanovatatiana86@yandex.ru
researcher, Laboratory for Molecular Diagnostics of Reproductive Tract Infections

T. Dolgova

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare

Email: tamara.dolgova89@gmail.com
junior researcher, Laboratory for Molecular Diagnostics of Reproductive Tract Infections

E. Goloveshkina

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare

Email: elenagoloveshkina@yandex.ru
PhD, junior researcher, Laboratory for Molecular Diagnostics of Reproductive Tract Infections

A. Gushchin

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare

Email: aguschin1965@pcr.ru
PhD, Head of the Laboratory for Molecular Diagnostics of Reproductive Tract Infections

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