Correction of isthmicocervical insufficiency in amniotic sac prolapse


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Abstract

The paper gives the results of clinically using an algorithm for managing women with isthmicocervical insufficiency (ICI) complicated by amniotic sac prolapse into the cervical canal or the upper third of the vagina at 24-26 weeks’ gestation. After taking into account all contraindications, in 17 cases atosiban tocolysis and antibiotic therapy were initiated, after which surgical correction of ICI was made, by tucking the amniotic sac behind the internal cervical os. Atosiban tocolysis was continued for 48 hours; fetal respiratory distress syndrome was prevented. In 14 (82.4%) of the 17 cases, pregnancy ended in timely deliveries at 37-39 weeks’ gestation. In 3 cases, preterm delivery occurred at 29, 32, and 34 weeks; the babies underwent a cycle of treatment and rehabilitation. The use of atosiban in the combination treatment of complicated ICI at 24-26 weeks’ gestation may become one of the options to prevent very early preterm delivery.

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About the authors

Nana K. Tetruashvili

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: tetrauly@mail.ru
Doctor of Medicine, Head of the Department of Pregnancy Loss Prevention and Therapy

Anna Aramovna Agadzhanova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: tetrauly@mail.ru
MD, Leading Researcher, Second Obstetric Department of Pregnancy Pathology

Asiya Kamilevna Milusheva

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_milusheva@oparina4.ru
obstetrician-gynecologist, Second Obstetric Department of Pregnancy Pathology

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