Pregnancy and childbirth in a patient with myelodysplastic syndrome


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Background. As of now, progress in therapy has frequently made it possible to plan pregnancy and safe childbirth in women with different hematological diseases. Myelodysplastic syndrome (MDS) is a group of severe clonal hematopoietic diseases that are most common in the old age group. Pregnancy in patients with MDS is extremely rare and associated with an increased risk of both maternal and fetal complications. Case report. The paper describes a case of successful pregnancy and childbirth in a 30-year-old patient with partial remission of refractory anemia with excess of blasts. Conclusion. Adequate initial therapy for the underlying disease, planning, and careful interdisciplinary follow-up throughout the gestation has promoted a favorable pregnancy outcome.

Full Text

Restricted Access

About the authors

Roman Georgievich Shmakov

Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: r_shmakov@oparina4.ru
M.D., Head Physician

Maria Alekseevna Vinogradova

Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: m_vinogradova@oparina4.ru
Ph.D, Head of reproductive hematology and hemostasia department

Evgenia Sergeevna Polushkina

Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: epolushkina@mail.ru
Ph.D, Researcher, Obstetrical Physiologic Department

Elena Vasilevna Kozyrko

Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: lenochka525@gmail.com
Researcher, Obstetrical Physiologic Department

References

  1. Савченко В.Г., ред. Программное лечение заболеваний системы крови. Сборник алгоритмов диагностики и протоколов лечения заболеваний системы крови. М.: Практика; 2012. 1056с. [Savchenko V.G., ed. Software treatment of diseases of the blood system. Collection of diagnostic algorithms and protocols, treatment of diseases of the blood system. Moscow: Praktika; 2012. 1056p. (in Russian)]
  2. Кохно А.В., Паровичникова Е.Н., Савченко В.Г. Миелодиспластический синдром. Клиническая геронтология. 2009; 15(3): 33-46. [Kohno A.V., Parovichnikova E.N., Savchenko V.G. Myelodysplastic syndrome. Klinicheskaya gerontologiya. 2009; 15 (3): 33-46. (in Russian)]
  3. Schanz J., Tüchler H., Solé F., Mallo M., Luno E., Cervera J. et al. New comprehensive cytogenetic scoring system for primary myelodysplastic syndromes (MDS) and oligoblastic acute myeloid leukemia after MDS derived from an international database merge. J. Clin. Oncol. 2012; 30(8): 820-9. doi: 10.1200/ JCO.2011.35.6394.
  4. Al-Ameri A., Cherry M., Garcia-Manero G., Quintás-Cardama A. Standard therapy for patients with myelodysplastic syndromes. Clin. Lymphoma Myeloma Leuk. 2011; 11(4): 303-13. doi: 10.1016/j.clml.2011.06.008.
  5. NCCN Clinical Practice Guidelines in Oncology. Myelodysplastic syndromes v 1.2012. Available at: http://www.nccn.org/professionals/ physician_gls/pdf/ mds.pdf Accessed March 9, 2012.
  6. Yang Z., Mei-Ying L., Shan-Mi W., Xiao-Hui Z. Pregnancy and myelodys-plastic syndrome: an analysis of the clinical characteristics, maternal and fetal outcomes. J. Matern. Fetal Neonatal Med. 2015; 28(18): 2155-9. doi: 10.3109/14767058.2014.980229.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2016 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies