Cerebral hemodynamic changes in different forms of hypertension in the third trimester of pregnancy
- Authors: Khramchenko N.V.1, Voevodin S.M.1, Andronova N.V.1
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Affiliations:
- Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
- Issue: No 4 (2017)
- Pages: 81-86
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/247891
- DOI: https://doi.org/10.18565/aig.2017.4.81-6
- ID: 247891
Cite item
Open Access
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Abstract
Objective. To investigate cerebral hemodynamics in pregnant women with hypertension. Subjects and methods. Cerebral hemodynamic parameters in the middle cerebral artery (MCA) and Rosenthal veins were investigated in 100 women with manifestations of hypertension occurring during pregnancy: in those with severe preeclampsia (PE) (n = 20), moderate PE (n = 35), and gestational hypertension (GH) (n = 45), or physiological pregnancy (n = 74). Regression analysis revealed the critical values of MCA pulsatility index (PI), which corresponded to severe PE. Results. The values of MCA мaximum blood flow velocity were higher in all the groups of pregnant women with hypertension than those in the control group: 170.5±19.4 cm/sec in the pregnant women with GH, 140.8±19.4 cm/sec in those with severe PE, and 121.4± 23.4 cm/sec in those with moderate PE. The distinguishing characteristic of both moderate and severe PE from GH was the values of MCA PI: lower PI values in PE (0.68±0.09 and 0.61±0.07, respectively) and higher PI values in GH (0.98±0.14). Conclusion. Transcranial Doppler ultrasonography allows identification of patients with critical cerebrovascular events.
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About the authors
Natalia V. Khramchenko
Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: n_khramchenko@oparina4.ru
head of the Department of Echography and Prenatal Diagnostics
Sergey M. Voevodin
Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: v_voevodin@oparina4.ru
Head of the Visual Diagnostics Department
Natalia V. Andronova
Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: andronowa@mail.ru
a geneticist
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