Correction of mastalgia and hyperprolactinaemia in women in perimenopause


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Objective. To evaluate the efficacy of mastodynon in eliminating complaints of mastalgia and in reducing hyperprolactinemia. Subjects and methods. After informed consent was obtained, 66 perimenopausal patients with complaints of breast pain and engorgement were divided into two groups: 1) 45 patients took mastodynon; 2) 21 patients received diclofenac rectal suppositories. During a follow-up, the patients kept diaries (indicating the severity of mastalgia, possible side effects of therapy). All the patients underwent clinical examination, breast ultrasound and mammography. Serum prolactin levels were measured before and 3 and 6 months after treatment. Resu1ts. Mastodynon treatment showed a positive clinical effect that was characterized by a reduction in pain syndrome and normalization of the hormone to the average value. Prolactin levels in the control group remained unchanged during the study. Conclusion. The data of the investigation have confirmed the possibility of effectively using mastodynon in perimenopausal women. The drug is safe and well tolerated.

Full Text

Restricted Access

About the authors

Galina Anatolyevna Lazareva

Kursk State Medical University

Email: galinal2007@yandex.ru
MD, professor of the Obstetrics and Gynecology Department

References

  1. Jatoi Ismail, Kaufmann M. eds. Management of breast diseases. New York: Springer; 2009. 671р.
  2. Огнерубов Н.А., Кушлинский Н.Е., Ткачева И.А. Клинические и эндокринологические исследования при мастопатии и раке молочной железы. Воронеж: Истоки; 1998. 176с. [Ognerubov N.A., Kushlinskiy N.E., Tkacheva I.A. Clinical and endocrinological studies in mastopathy and breast cancer. Voronezh: Istoki; 1998. 176p. (in Russian)]
  3. Сметник В.П., Тумилович Л.Г. Неоперативная гинекология. М.: МИА; 2001. [Smetnik V.P., Tumilovich L.G. Non-operative gynecology. Moscow: MIA; 2001. (in Russian)]
  4. Семиглазов В.Ф., Веснин А.Г., Моисеенко В.М. Минимальный рак молочной железы (профилактика, выявление, лечение). СПб.: Гиппократ; 2009. 240с. [Semiglazov V.F., Vesnin A.G., Moiseenko V.M. Minimal breast cancer (prevention, detection, treatment). St. Petersburg: Hippocrates; 2009. 240p. (in Russian)]
  5. Летягин В.П. Мастопатия. Русский медицинский журнал. 2000; 8(11): 46873. [Letyagin V.P. Mastopathy. Russian medical journal. 2000; 8(11): 468-73. (in Russian)]

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2017 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies