Correction of mastalgia and hyperprolactinaemia in women in perimenopause

Objective. To evaluate the efficacy of mastodynon in eliminating complaints of mastalgia and in reducing hyperprolactinemia. Subjects and methods. After informed consent was obtained, 66 perimenopausal patients with complaints of breast pain and engorgement were divided into two groups: 1) 45 patients took mastodynon; 2) 21 patients received diclofenac rectal suppositories. During a follow-up, the patients kept diaries (indicating the severity of mastalgia, possible side effects of therapy). All the patients underwent clinical examination, breast ultrasound and mammography. Serum prolactin levels were measured before and 3 and 6 months after treatment. Resu1ts. Mastodynon treatment showed a positive clinical effect that was characterized by a reduction in pain syndrome and normalization of the hormone to the average value. Prolactin levels in the control group remained unchanged during the study. Conclusion. The data of the investigation have confirmed the possibility of effectively using mastodynon in perimenopausal women. The drug is safe and well tolerated.

mastalgia, prolactin, mastopathy, mastodynon